ArticleJMIR public health and surveillance2024
Investigation of Mother-to-Child Transmission of Hepatitis B in Yinchuan, China: Cross-Sectional Survey Study.
Article in JMIR public health and surveillance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Real-world efficacy of comprehensive measures against mother-to-child transmission of HBV in south-eastern Jiangsu, China.BMC infectious diseases · 2026Article
- Knowledge, perceptions, and health education needs regarding hepatitis B virus among HBsAg-positive pregnant women in Taiyuan, China: a cross-sectional study.BMC public health · 2025Article
- Global burden, trends and inequalities of hepatitis B among women of childbearing age, 1990-2021.Annals of medicine · 2025Article
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7 authors.
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Abstract
backgroundHepatitis B poses a significant global public health challenge, with mother-to-child transmission (MTCT) being the primary method of hepatitis B virus (HBV) transmission. The prevalence of HBV infection in China is the highest in Asia, and it carries the greatest burden globally.
objectiveThis study aims to critically evaluate the existing local strategies for preventing MTCT and the proposed potential enhancements by analyzing the prevalence of hepatitis B among pregnant women and their neonates in Yinchuan.
methodsFrom January 2017 to December 2021, 37,557 prenatal screening records were collected. Among them, 947 pregnant women who tested positive for hepatitis B surface antigen (HBsAg) near delivery and their 960 neonates were included in an HBV-exposed group, while 29 pregnant women who tested negative and their 30 neonates were included in an HBV-nonexposed group. HBV markers in maternal peripheral blood and neonatal cord blood were analyzed using the least absolute shrinkage and selection operator (LASSO) regression, logistic regression, chi-square test, t-test, and U-test. Additionally, to further evaluate the diagnostic value of HBsAg positivity in cord blood, we conducted an additional follow-up study on 103 infants who tested positive for HBsAg in their cord blood.
resultsThe prevalence of HBV among pregnant women was 2.5% (947/37,557), with a declining trend every year (χ²
conclusionsThe clinical relevance of HBV marker detection in cord blood is restricted within the current prevention measures for MTCT. There is an emphasis on the significance of public education regarding hepatitis B and the reinforcement of postnatal follow-up for the prevention of MTCT.
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