Evidence map›Paper›PMID 39230854›Full record

ReviewAnnals of surgical oncology2024

Comprehensive Review of Future Liver Remnant (FLR) Assessment and Hypertrophy Techniques Before Major Hepatectomy: How to Assess and Manage the FLR.

Mehdi Boubaddi, Arthur Marichez, Jean-Philippe Adam, Bruno Lapuyade, Frederic Debordeaux, Ghoufrane Tlili, Laurence Chiche, Christophe Laurent

Abstract readReview
PubMed Publisher
In one paragraph

Review in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. [Role of Kupffer cells in liver regeneration with metabolic associated fatty liver disease in mice].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Prognostic Impact of Diabetes Mellitus and Extended Hepatectomy on Perihilar Cholangiocarcinoma.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mehdi BoubaddiHepatobiliary and Pancreatic Surgery Department, Bordeaux University Hospital Center, Bordeaux, France. mehdi.boubaddi@gmail.com.ORCID http://orcid.org/0000-0003-2016-6369
Arthur MarichezHepatobiliary and Pancreatic Surgery Department, Bordeaux University Hospital Center, Bordeaux, France.
Jean-Philippe AdamHepatobiliary and Pancreatic Surgery Department, Bordeaux University Hospital Center, Bordeaux, France.
Bruno LapuyadeRadiology Department, Bordeaux University Hospital Center, Bordeaux, France.
Frederic DebordeauxNuclear Medicine Department, Bordeaux University Hospital Center, Bordeaux, France.
Ghoufrane TliliNuclear Medicine Department, Bordeaux University Hospital Center, Bordeaux, France.
Laurence ChicheHepatobiliary and Pancreatic Surgery Department, Bordeaux University Hospital Center, Bordeaux, France.
Christophe LaurentHepatobiliary and Pancreatic Surgery Department, Bordeaux University Hospital Center, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe regenerative capacities of the liver and improvements in surgical techniques have expanded the possibilities of resectability. Liver resection is often the only curative treatment for primary and secondary malignancies, despite the risk of post-hepatectomy liver failure (PHLF). This serious complication (with a 50% mortality rate) can be avoided by better assessment of liver volume and function of the future liver remnant (FLR).

objectiveThe aim of this review was to understand and assess clinical, biological, and imaging predictors of PHLF risk, as well as the various hypertrophy techniques, to achieve an adequate FLR before hepatectomy.

methodWe reviewed the state of the art in liver regeneration and FLR hypertrophy techniques.

resultsThe use of new biological scores (such as the aspartate aminotransferase/platelet ratio index + albumin-bilirubin [APRI+ALBI] score), concurrent utilization of

conclusionThere is a need to standardize volumetry and function measurement techniques, as well as FLR hypertrophy techniques, to limit the risk of PHLF.

Indexed as

HepatectomyLiverLiver NeoplasmsLiver RegenerationHumansHypertrophyLiver FailureOrgan SizePostoperative ComplicationsPrognosisALPPSFuture liver remnantLiver hypertrophyLiver regenerationLiver venous deprivationLVDPHLFPortal vein embolization

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.