Neuropsychiatric Symptoms in Rhombencephalosynapsis: A Clinical Report.

Dennis J L G Schutter, Dan Doherty, James O Phillips, Avery H Weiss, Roderick P P W M Maas

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In one paragraph

Article in Cerebellum (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dennis J L G SchutterDepartment of Experimental Psychology, Helmholtz Institute, Utrecht University, Heidelberglaan 1, Utrecht, 3584 CS, the Netherlands. d.j.l.g.schutter@uu.nl.

Dan DohertyDepartment of Pediatrics, University of Washington School of Medicine, Seattle, USA.

James O PhillipsDepartment of Otolaryngology, University of Washington School of Medicine, Seattle, USA.

Avery H WeissDepartment of Ophthalmology, University of Washington School of Medicine, Seattle, USA.

Roderick P P W M MaasDepartment of Neurology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek VI.C.181.005

6 · The paper itself

Abstract

Rhombencephalosynapsis (RES) is a hindbrain malformation characterized by a missing cerebellar vermis with apposition or fusion of the cerebellar hemispheres. The present clinical case report provides a comprehensive, longitudinal overview of cognitive and affective manifestations in a 22-year-old patient with RES. The patient shows clinical signs of emotional reactivity and dysregulation, impulsivity, and impairments in executive functioning since early childhood. These features fit the constellation of neuropsychiatric symptoms observed in patients with congenital and acquired abnormalities of the posterior vermis. It is proposed that patients with RES may show affective and cognitive difficulties which increase their vulnerability to psychological stress and risk of developing mental health issues.

Indexed as

RhombencephalonCerebellumHumansMagnetic Resonance ImagingYoung AdultCerebellar Cognitive Affective SyndromeEmotionExecutive FunctioningPsychopathologyVermis

Identifiers

PMID39230845

DOI10.1007/s12311-024-01740-8

PMCPMC11585500

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.