Evidence map›Paper›PMID 39230796›Full record

ArticleCardiovascular engineering and technology2024

Feasibility Testing of the Bionet Sonar Ultrasound Transcutaneous Energy Transmission (UTET) System for Wireless Power and Communication of a LVAD.

Gretel Monreal, Steven C Koenig, Amit Sangwan, Raffaele Guida, Jiapeng Huang, Emrecan Demirors, Tommaso Melodia, Jorge H Jimenez, Mark S Slaughter

Abstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gretel Monreal *Department of Cardiovascular and Thoracic Surgery, University of Louisville, 302 E. Muhammad Ali Blvd, room 411, Louisville, KY, 40202, USA. gretel.monreal@louisville.edu.ORCID 0000-0002-6576-738X
Steven C Koenig *Department of Cardiovascular and Thoracic Surgery, University of Louisville, 302 E. Muhammad Ali Blvd, room 411, Louisville, KY, 40202, USA.
Amit SangwanBionet Sonar Inc., Burlington, MA, USA.
Raffaele GuidaBionet Sonar Inc., Burlington, MA, USA.
Jiapeng HuangDepartment of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, KY, USA.
Emrecan DemirorsBionet Sonar Inc., Burlington, MA, USA.
Tommaso MelodiaBionet Sonar Inc., Burlington, MA, USA.
Jorge H JimenezBionet Sonar Inc., Burlington, MA, USA.
Mark S SlaughterDepartment of Cardiovascular and Thoracic Surgery, University of Louisville, 302 E. Muhammad Ali Blvd, room 411, Louisville, KY, 40202, USA.

Funding

University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
Research Design, Compliance, and Data Management (RDCD)P20GM155899 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Kelli Matheson Bullard Dunn · 2024 to 2026
$9.3M
Cavopulmonary Assist to Reverse the FontanR01HL150346 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI RODEFELD, MARK D · 2020 to 2023
$8.9M
Development of the Inspired Therapeutics NeoMate Mechanical Circulatory Support System for Neonates and InfantsR44HL144214 · NHLBI · INSPIRED THERAPEUTICS, LLC · PI TAMEZ, DANIEL · 2022 to 2025
$6.1M
Low Density Neutrophils Link Inflammation and Coagulopathy in COVID-19R01HL158779 · NHLBI · UNIVERSITY OF LOUISVILLE · PI HUANG, JIAPENG, URIARTE, SILVIA M · 2022 to 2025
$2.9M
Neutrophil Heterogeneity and Immunopathogenesis of COVID-19 ARDSR01AI172873 · NIAID · UNIVERSITY OF LOUISVILLE · PI Jiapeng Huang, Silvia M Uriarte · 2023 to 2026
$2.3M
A Handheld Microchip for GC analysis of breath to screen for COVID-19U18TR003787 · NCATS · UNIVERSITY OF LOUISVILLE · PI FU, XIAO-AN, NANTZ, MICHAEL H · 2021 to 2022
$2.0M
Development of an intravascular circulatory support device for high-risk for percutaneous coronary intervention and cardiogenic shockR43HL152774 · NHLBI · RT CARDIAC SYSTEMS, INC. · PI LAROSE, JEFFREY · 2020 to 2020
$492k
Wireless ultrasonic powering and monitoring of Left Ventricular Assist Devices through the Internet of Medical ThingsR43HL152767 · NHLBI · BIONET SONAR · PI JIMENEZ, JORGE HERNAN · 2020 to 2020
$469k
Enabling of a wireless and remotely monitored bi-ventricular pacing device through the internet of medical things for heart failure patientsR43HL149451 · NHLBI · BIONET SONAR · PI JIMENEZ, JORGE HERNAN · 2020 to 2020
$444k
Enabling of a Wireless and Remotely Monitored Deep Brain Stimulation System through the Internet of Medical Things for Parkinson's Disease PatientsR43NS115226 · NINDS · BIONET SONAR · PI JIMENEZ, JORGE HERNAN · 2019 to 2019
$329k
Left atrial appendage closure device with catheter-based delivery for patients with non-valvular atrial fibrillationR43HL142337 · NHLBI · COR HABERE CORPORATION · PI JIMENEZ, JORGE HERNAN · 2018 to 2018
$311k
NCATS NIH HHS U18 TR003787NHLBI NIH HHS R01 HL150346NHLBI NIH HHS R01 HL158779NHLBI NIH HHS R43 HL142337NHLBI NIH HHS R43 HL142385NHLBI NIH HHS R43 HL149451NHLBI NIH HHS R43 HL152767NHLBI NIH HHS R43 HL152774NHLBI NIH HHS R43 HL152894NHLBI NIH HHS R44 HL144214NIAID NIH HHS R01 AI172873NIEHS NIH HHS P30 ES030283NIGMS NIH HHS P20 GM155899NIH HHS R43HL152767NINDS NIH HHS R43 NS115226
6 · The paper itself

Abstract

purposeTo address the clinical need for totally implantable mechanical circulatory support devices, Bionet Sonar is developing a novel Ultrasonic Transcutaneous Energy Transmission (UTET) system that is designed to eliminate external power and/or data communication drivelines.

methodsUTET systems were designed, fabricated, and pre-clinically tested using a non-clinical HeartWare HVAD in static and dynamic mock flow loop and acute animal models over a range of pump speeds (1800, 2400, 3000 RPM) and tissue analogue thicknesses (5, 10, 15 mm).

resultsThe prototypes demonstrated feasibility as evidenced by meeting/exceeding function, operation, and performance metrics with no system failures, including achieving receiver (harvested) power exceeding HVAD power requirements and data communication rates of 10kB/s and pump speed control (> 95% sensitivity and specificity) for all experimental test conditions, and within healthy tissue temperature range with no acute tissue damage.

conclusionDuring early-stage development and testing, engineering challenges for UTET size reduction and stable and safe operation were identified, with solutions and plans to address the limitations in future design iterations also presented.

Indexed as

Feasibility StudiesHeart-Assist DevicesProsthesis DesignWireless TechnologyAnimalsElectric Power SuppliesEquipment DesignVentricular Function, LeftDrivelineDriveline infectionHeart failureLeft ventricular assist deviceMechanical circulatory supportTranscutaneous energy transmission systemUltrasonic wide bandWireless

Identifiers

PMID39230796
PMCPMC12318372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.