Evidence map›Paper›PMID 39230724›Full record

ArticleJournal of neurology2024

Mimickers of nervous system involvement among patients with Behçet's syndrome.

Elif Dincses Nas, E Buse Caliskan, Z Ece Kaya Gulec, Ugur Uygunoglu, Melih Tutuncu, Sabahattin Saip, Aksel Siva, Gulen Hatemi

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Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Elif Dincses NasSchool of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
E Buse CaliskanSchool of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Z Ece Kaya GulecSchool of Medicine, Department of Neurology, Istanbul University-Cerrahpasa, Istanbul, 34098, Turkey.
Ugur UygunogluSchool of Medicine, Department of Neurology, Istanbul University-Cerrahpasa, Istanbul, 34098, Turkey. uguruygunoglu@gmail.com.ORCID http://orcid.org/0000-0003-2866-4004
Melih TutuncuSchool of Medicine, Department of Neurology, Istanbul University-Cerrahpasa, Istanbul, 34098, Turkey.
Sabahattin SaipSchool of Medicine, Department of Neurology, Istanbul University-Cerrahpasa, Istanbul, 34098, Turkey.
Aksel SivaSchool of Medicine, Department of Neurology, Istanbul University-Cerrahpasa, Istanbul, 34098, Turkey.
Gulen HatemiSchool of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to identify conditions mimicking nervous system involvement among patients with Behçet's syndrome (BS) and to determine clinical, laboratory and imaging findings that may help in the differential diagnosis.

methodsWe screened the charts of 500 consecutive BS patients to identify those who were referred to neurology at any time during their follow-up. The final diagnoses, presenting signs and symptoms, laboratory and imaging results were retrieved from patient charts. Patients who did not have a follow-up visit during the last 3 months were invited to the clinic.

resultsAmong the 500 BS patients, 116 (23%) had been referred to neurology. Among these, 29 (5.8%) were diagnosed with typical central nervous system involvement of BS (NeuroBS). The type of NeuroBS was parenchymal involvement in 21 patients, cerebral venous sinus thrombosis in 7 patients, and both in 1 patient. 30 patients (6%) had other conditions related to the nervous system, 46 (9.2%) did not have a nervous system disorder, and their symptoms recovered spontaneously, and 11 (2.2%) were lost to follow-up without a definite diagnosis. Of the 30 BS patients who were diagnosed with another nervous system condition, 14 (46%) had primary headache syndromes, 6 (20%) had psychiatric disorders, 2 had entrapment neuropathy, and 1 each had epilepsy, glial tumor, multiple sclerosis, Meniere's disease, optic neuritis, neuroretinitis, steroid myopathy and polyneuropathy.

conclusionNervous system conditions other than NeuroBS are frequent among BS patients referred to neurology. Caution is required to avoid misdiagnosis of these patients as NeuroBS.

Indexed as

Behcet SyndromeAdolescentAdultCentral Nervous System DiseasesDiagnosis, DifferentialFemaleHumansMaleMiddle AgedNervous System DiseasesRetrospective StudiesYoung AdultBehçet’s syndromeCerebral venous sinus thrombosisNervous systemNeurologic involvement

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.