Evidence map›Paper›PMID 39230672›Full record

ArticleCardiovascular and interventional radiology2024

Two-Year Outcomes of Prostatic Artery Embolization for Symptomatic Benign Prostatic Hyperplasia: An International, Multicenter, Prospective Study.

Marc R Sapoval, Shivank Bhatia, Carole Déan, Antonio Rampoldi, Francisco César Carnevale, Clare Bent, Charles R Tapping, Simone Bongiovanni, Jeremy Taylor, Jayson S Brower and 4 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Cardiovascular and interventional radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03527589 (A Prospective Post Market Study of Patients With Symptomatic Benign Prostatic Hyperplasia Treated by Prostatic Artery Embolization With Embosphere® Microspheres), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03527589 completednot on this map

A Prospective Post Market Study of Patients With Symptomatic Benign Prostatic Hyperplasia Treated by Prostatic Artery Embolization With Embosphere® Microspheres

Typeobservational_patient_registrySponsorMerit Medical Systems, Inc.Ran2018 to 2022Enrolled499ConditionsBenign Prostatic Hyperplasia, Lower Urinary Tract SymptomsArmsProstate artery embolization
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marc R SapovalDepartment of Vascular and Oncological Interventional Radiology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, 20 Rue Leblanc, 75015, Paris, France. marc.sapoval2@aphp.fr.
Shivank BhatiaDepartment of Interventional Radiology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Carole DéanDepartment of Vascular and Oncological Interventional Radiology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, 20 Rue Leblanc, 75015, Paris, France.
Antonio RampoldiDepartment of Interventional Radiology, Ospedale Niguarda Ca' Granda, Milan, Italy.
Francisco César CarnevaleDepartment of Radiology, Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Clare BentDepartment of Interventional Radiology, Royal Bournemouth and Christchurch Hospital, Bournemouth, UK.
Charles R TappingDepartment of Radiology, The Churchill Hospital, Oxford, UK.
Simone BongiovanniDepartment of Radiology, Azienda Ospedaliera S. Croce E Carle, Cuneo, Italy.
Jeremy TaylorDepartment of Interventional Radiology, Frimley Park Hospital, Surrey, UK.
Jayson S BrowerDepartment of Radiology, Providence Sacred Heart, Spokane, WA, USA.
Michael RushHoly Cross South Florida Medical Imaging, Fort Lauderdale, FL, USA.
Justin P McWilliamsDivision of Interventional Radiology, Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Mark W LittleUniversity Department of Radiology, Royal Berkshire Hospital, Reading, UK.
PROstate Study Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe clinical outcomes among patients with benign prostatic hyperplasia (BPH) 24 months following prostatic artery embolization (PAE). MATERIALS AND

methodsThis was an international, multicenter, prospective trial of males with BPH with lower urinary tract symptoms (LUTS) or acute urinary retention (AUR) treated with PAE. The primary outcome was the 12 month change in the International Prostate Symptom Score (IPSS) for patients referred for bothersome LUTS, or urinary catheter independence for patients treated for AUR. Secondary outcome measures included changes in IPSS at 3 and 24 months, changes in quality of life (QoL), changes in the Sexual Health Inventory for Men (SHIM) questionnaire, technical success rate, and adverse events (AEs). Data were summarized using descriptive statistics.

resultsFour hundred seventy-eight consecutive patients underwent PAE (bothersome LUTS: N = 405; AUR: N = 73), mean age was 70 years. For patients treated for bothersome LUTS, mean total IPSS at baseline was 21.8 and decreased to 9.3, 10.6, and 11.2 at 3, 12, and 24 months following PAE, respectively (all p < 0.001); QoL at baseline was 4.7 and decreased to 2.0, 2.1, and 2.3 at 3, 12, and 24 months, respectively (all p < 0.001). The mean SHIM score at baseline and 12 months following PAE was 13.8 and 13.9, respectively. Of the 73 patients treated for AUR, 48 (65.8%) had their indwelling catheter removed within 3 months of PAE and remained catheter free at 24 months. Fifty-five patients (11.5%) experienced ≥ 1 AE and 10 (2.1%) experienced a serious AE.

conclusionPAE is a safe and effective treatment for symptomatic BPH and LUTS. Level of Evidence Level 3 Trial registration ClinicalTrials.gov NCT03527589.

Indexed as

Embolization, TherapeuticProstateProstatic HyperplasiaQuality of LifeAgedAged, 80 and overHumansLower Urinary Tract SymptomsMaleMiddle AgedProspective StudiesRegistriesSurveys and QuestionnairesTreatment OutcomeUrinary RetentionAcute urinary retentionBenign prostatic hyperplasiaEmbosphere® MicrospheresInternational Prostate Symptom Score (IPSS)Lower urinary tract symptomsProstatic artery embolizationQuality of lifeSexual Health Inventory for Men (SHIM)

Identifiers

PMID39230672
PMCPMC11541243

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.