Evidence map›Paper›PMID 39230147›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2024

Serologic screening for viral infections among blood donors: a study in a blood bank in southern Brazil.

Gabriella Shinmi Belanda, Mariana Fardin, Thelma Larocca Skare, Claudia Alexandra Pontes Ivantes, Karla Braga Fávero, Paulo Tadeu Rodrigues Alemida, Mateus Oliveiro de Almeida, Renato Nisihara

Abstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabriella Shinmi BelandaMackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0002-3524-4086
Mariana FardinMackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.ORCID http://orcid.org/0009-0007-7245-8810
Thelma Larocca SkareMackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0002-7699-3542
Claudia Alexandra Pontes IvantesUniversidade Federal do Paraná, Department of Medical Clinic - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0001-5422-557X
Karla Braga FáveroInstitute of Hematology, Hemobanco - Curitiba (PR), Brazil.ORCID http://orcid.org/0009-0004-9752-3699
Paulo Tadeu Rodrigues AlemidaInstitute of Hematology, Hemobanco - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0003-3067-0040
Mateus Oliveiro de AlmeidaInstitute of Hematology, Hemobanco - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0001-8332-2555
Renato NisiharaMackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.ORCID http://orcid.org/0000-0002-1234-8093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoutine screening for viral infections at blood donation is important to avoid transfusion-transmitted infections. It also offers an opportunity to detect an asymptomatic infection.

objectiveTo study changes in serology positivity for viral infections (B and C hepatitis, HTLV-1/2, and HIV) at blood donation in a blood bank from Southern Brazil, comparing two periods of 5 years: the period from 2013 to 2017 with the period from 2018 to 2022. In addition, data on the donor fidelity rate during the studied period were sought.

methodsRetrospective study using data from 2013 to 2022 from a single blood center electronic database from Curitiba, Southern Brazil.

resultsA significant drop in positive serology for all studied viruses was observed: highest in HIV (OR=0.39; 95% CI=0.27-0.57) and lowest in total anti HBc (0.56; 95 CI=0.50-0.63). Anti HBc serology became more commonly seen in women in the period of 2018-2022 when compared to men. No changes in the distribution of positive serology according to donors' ages were observed. Loyalty rates had a median of 70%, with the lowest being 60% in 2013, while the highest was 73% in 2018 and 2022.

conclusionA significant reduction in discarded blood bags due to viral serology was observed when the period of 2013-2017 was compared to 2018-2022 on this blood bank; the highest reduction was observed in HIV serology and the lowest in HBc serology, which became more common in women in the second period. High rates of donor fidelity were observed during the period studied.

Indexed as

Blood BanksBlood DonorsAdolescentAdultBrazilFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleMass ScreeningMiddle AgedRetrospective StudiesSerologic TestsVirus Diseases

Identifiers

PMID39230147
PMCPMC11370740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.