Evidence map›Paper›PMID 39229962›Full record

ReviewGut microbes

Benefits and concerns of probiotics: an overview of the potential genotoxicity of the colibactin-producing

Luca Falzone, Alessandro Lavoro, Saverio Candido, Mario Salmeri, Antonino Zanghì, Massimo Libra

Abstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  12. Review
  13. Review
  14. Article
  15. Probiotic biogeography and sepsis prevention in the neonatal intestine.bioRxiv : the preprint server for biology · 2025
    Article
  16. Remote control designer probiotics.Nature microbiology · 2025
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luca FalzoneDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.ORCID 0000-0001-7349-6826
Alessandro LavoroDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Saverio CandidoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Mario SalmeriDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Antonino ZanghìDepartment of Medical and Surgical Sciences and Advanced Technology 'G.F. Ingrassia', University of Catania, Catania, Italy.
Massimo LibraDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the mounting integration of probiotics into human health strategies has gathered considerable attention. Although the benefits of probiotics have been widely recognized in patients with gastrointestinal disorders, immune system modulation, and chronic-degenerative diseases, there is a growing need to evaluate their potential risks. In this context, new concerns have arisen regarding the safety of probiotics as some strains may have adverse effects in humans. Among these strains,

Indexed as

Escherichia coliPeptidesPolyketidesProbioticsAnimalsDNA DamageHumansMutagensPolyketide SynthasescolibactinMutagensPeptidesPolyketidesPolyketide SynthasesColibactinCRCEcNEscherichia coli Nissle 1917GenotoxicityGut microbiotapks locusPostbioticsProbioticsprobiotic safety

Identifiers

PMID39229962
PMCPMC11376418

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.