Evidence map›Paper›PMID 39229890›Full record

ReviewUnited European gastroenterology journal2024

Recent advances in the treatment of refractory gastrointestinal angiodysplasia.

Aymeric Becq, Reena Sidhu, Lia C M J Goltstein, Xavier Dray

Abstract readReview
In one paragraph

Review in United European gastroenterology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Taiwan practical consensus for evaluation and management of small-bowel bleeding.Journal of the Chinese Medical Association : JCMA · 2026
    Guideline
  2. Trial
  3. Undetected Gastric Angiodysplastic Lesion Causing Obscure Gastrointestinal Bleeding.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aymeric BecqGastroenterology Department, Paris-Est Créteil University, Henri Mondor Hospital, AP HP, Créteil, France.ORCID 0000-0003-4637-9012
Reena SidhuDivision of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Lia C M J GoltsteinDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Xavier DraySorbonne University, Center for Digestive Endoscopy, Saint Antoine Hospital, AP HP, Paris, France.ORCID 0000-0002-4527-203X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal angiodysplasia (GIA) is a common, acquired, vascular abnormality of the digestive tract, and a frequent cause of bleeding. Refractory GIA criteria usually include recurrent bleeding, transfusions and/or repeat endoscopy. Pharmacological and interventional treatments have been the subject of recent high-quality publications. This review provides an overview of the latest updates on non-endoscopic management of refractory GIA. Aortic valve replacement has shown its efficacy in Heyde syndrome and should be considered if indicated. Anti-angiogenic drugs, such as Octreotide and Thalidomide, are efficient treatments of refractory GIA-related bleeding. Somatostatin analogs should, based on efficacy and tolerance profile, be considered first. In the future, a better understanding of the physiopathology of GIA might help develop new-targeted therapies.

Indexed as

AngiodysplasiaAngiogenesis InhibitorsGastrointestinal HemorrhageGastrointestinal AgentsHumansOctreotideSomatostatinThalidomideAngiogenesis InhibitorsGastrointestinal AgentsOctreotideSomatostatinThalidomideangiodysplasiaaortic valve replacementbevacizumabgastrointestinal bleedingsomatostatin analogsthalidomidetranscatheter aortic valve implantation

Identifiers

PMID39229890
PMCPMC11485408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.