Evidence map›Paper›PMID 39229811›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2024

Thio and Seleno Derivatives of Angelicin as Efficient Triplet Harvesting Photosensitizers: Implications in Photodynamic Therapy.

Pranay Mohanty, S Sarang, Saiprakash Rout, Himansu S Biswal

Abstract read
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pranay MohantySchool of Chemical Sciences, National Institute of Science Education and Research (NISER), PO-Bhimpur-Padanpur Via-Jatni, District-Khurda, PIN-752050, Bhubaneswar, India.
S SarangSchool of Chemical Sciences, National Institute of Science Education and Research (NISER), PO-Bhimpur-Padanpur Via-Jatni, District-Khurda, PIN-752050, Bhubaneswar, India.
Saiprakash RoutSchool of Chemical Sciences, National Institute of Science Education and Research (NISER), PO-Bhimpur-Padanpur Via-Jatni, District-Khurda, PIN-752050, Bhubaneswar, India.
Himansu S BiswalSchool of Chemical Sciences, National Institute of Science Education and Research (NISER), PO-Bhimpur-Padanpur Via-Jatni, District-Khurda, PIN-752050, Bhubaneswar, India.ORCID 0000-0003-0791-2259

Funding

Department of Atomic Energy, Science and Engineering Research BoardDepartment of Science and Technology CRG/2022/001096
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is widely accepted in medical practice for its targeted induction of apoptosis in cancerous cells. Angelicin (Ang) has traditionally been known for its efficacy in cancer treatment and its capability to enter a photoexcited triplet state. This study has comprehensively assessed the effects of substituting individual chalcogen atoms at three specific positions in Angelicin, with the objective of facilitating access to this elusive triplet state to enhance its role as a photosensitizer in PDT. The study scrutinizes various enhancements and factors that are crucial for efficient triplet harvesting. The decrease in singlet-triplet energy gap (ΔE

Indexed as

FurocoumarinsPhotochemotherapyPhotosensitizing AgentsMolecular StructureangelicinFurocoumarinsPhotosensitizing AgentsIntersystem CrossingPhotodynamic TherapyPhotosensitizersReactive Oxygen SpeciesTriplet Harvesting

Identifiers

PMID39229811
PMCPMC11648829

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.