Evidence map›Paper›PMID 39229478›Full record

ArticleHealth science reports2024

Control strategies for emerging infectious diseases: Crimean-Congo hemorrhagic fever management.

Shriyansh Srivastava, Sachin Kumar, Pramod Kumar Sharma, Sarvesh Rustagi, Aroop Mohanty, Suzanne Donovan, Andres F Henao-Martinez, Ranjit Sah, Carlos Franco-Paredes

Abstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shriyansh SrivastavaDepartment of Pharmacology Delhi Pharmaceutical Sciences and Research University (DPSRU) Sector 3 Pushp Vihar New Delhi India.ORCID 0000-0002-3738-4381
Sachin KumarDepartment of Pharmacology Delhi Pharmaceutical Sciences and Research University (DPSRU) Sector 3 Pushp Vihar New Delhi India.
Pramod Kumar SharmaDepartment of Pharmacy, School of Medical and Allied Sciences Galgotias University Greater Noida India.
Sarvesh RustagiSchool of Applied and Life Sciences Uttaranchal University Dehradun Uttarakhand India.
Aroop MohantyDepartment of Microbiology All India Institute of Medical Sciences Gorakhpur India.
Suzanne DonovanDepartment of Medicine David Geffen School of Medicine at UCLA Los Angeles California USA.
Andres F Henao-MartinezDivision of Infectious Diseases University of Colorado Anschutz Medical Campus Aurora Coloardo USA.
Ranjit SahDepartment of Microbiology Tribhuvan University Teaching Hospital, Institute of Medicine Kathmandu Nepal.
Carlos Franco-ParedesHospital Infantil de México, Federico Gómez, México; and Department of Microbiology, Immunology, and Pathology Colorado State University Fort Collins Colorado USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Crimean-Congo Hemorrhagic Fever (CCHF) is a significant public health concern transmitted by ticks. This study seeks to thoroughly grasp the epidemiology and transmission patterns of CCHF, which is caused by the CCHF virus (CCHFV), a member of the Nairovirus genus in the Bunyaviridae family. Methods: The study investigates the global distribution and endemicity of CCHF, its mortality rates, modes of transmission (including tick bites, contact with infected animal blood, and limited person-to-person transmission), and factors influencing its prevalence across different regions. Genetic diversity within CCHFV and its impact on transmission dynamics are explored, along with efforts to control the disease through tick prevention, antiviral treatment, and the development of vaccines and diagnostics. Results: CCHFV exhibits widespread distribution, particularly in the Middle East, Africa, Asia, and Eastern Europe, with an overall mortality rate of approximately 30% and a case fatality rate ranging from 10% to 40%. Transmission occurs primarily through tick bites and contact with infected animal blood, with limited person-to-person transmission. Livestock workers, slaughterhouse employees, and animal herders in endemic areas are most affected by their frequent interaction with sick animals and ticks. Genetic diversity within CCHFV contributes to variations in transmission dynamics, complicating control efforts. Antiviral ribavirin shows efficacy in treating CCHF infection. Conclusion: This study underscores the importance of further research to understand the enzootic environment, transmission routes, and genetic diversity of CCHFV for effective control measures, including the development of vaccines, treatment options, and diagnostics.

Indexed as

outbreak investigationpathophysiologypublic healthvector‐borne diseasesviral hemorrhagic feverszoonotic diseases

Identifiers

PMID39229478
PMCPMC11368823

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.