Evidence map›Paper›PMID 39229365›Full record

ArticleEuropean urology open science2024

Pelvic Lymph Node Dissection: A Comparison Among Extraperitoneal Single-port and Transperitoneal Multiport Radical Prostatectomy-A Single-center Experience.

Greta Pettenuzzo, Francesco Ditonno, Donato Cannoletta, Matteo Pacini, Luca Morgantini, Ruben Calvo Sauer, Juan R Torres-Anguiano, Francesco Montorsi, Alberto Briganti, Riccardo Bartoletti and 4 more

Abstract read
In one paragraph

Article in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Greta PettenuzzoDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Francesco DitonnoDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Donato CannolettaDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Matteo PaciniDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Luca MorgantiniDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Ruben Calvo SauerDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Juan R Torres-AnguianoDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.
Francesco MontorsiDivision of Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Alberto BrigantiDivision of Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Riccardo BartolettiUrology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Alessandro VecciaDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Riccardo BertoloDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Alessandro AntonelliDepartment of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Simone CrivellaroDepartment of Urology, University of Illinois at Chicago, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: The role of pelvic lymph node dissection (PLND) for prostate cancer is still controversial. This study aims to compare the outcomes of PLND between extraperitoneal single-port (SP eRARP) and transperitoneal multiport (MP tRARP) robotic-assisted radical prostatectomy. Methods: This was a retrospective analysis from our single-center database for patients who underwent SP eRARP or MP tRARP with PLND between 2015 and 2023. The primary endpoint was to analyze and compare specific data related to PLND between the two populations by the detection of pN+ patients, the total number of lymph nodes removed, and the number of positive lymph nodes removed. The secondary endpoints included comparing major complications, lymphoceles, and biochemical recurrence between the two cohorts of the study. Key findings and limitations: A total of 293 patients were included, with 85 (29%) undergoing SP eRARP and 208 (71%) undergoing MP tRARP. SP eRARP showed significant differences in PLND extension from MP tRARP, while MP tRARP yielded more lymph nodes ( Conclusions and clinical implications: Despite the SP approach in RARP resulting in fewer retrieved lymph nodes, outcomes were comparable with the MP approach regarding the detection of patients with positive lymph nodes and the number of positive nodes. Additionally, the SP approach led to lower pain levels and shorter hospital stays. Patient summary: With this study, we demonstrate that pelvic lymph node dissection performed via the extraperitoneal approach during robotic-assisted radical prostatectomy with a single-port system provides comparable outcomes with the standard transperitoneal multiport approach in detecting patients with positive lymph nodes and retrieving positive nodes. In addition, it offers significantly reduced pain levels and shorter hospital stays.

Indexed as

ExtraperitonealLymph node dissectionProstatectomyRobotic surgical procedures

Identifiers

PMID39229365
PMCPMC11369446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.