Evidence map›Paper›PMID 39229193›Full record

ArticlebioRxiv : the preprint server for biology2024

Bacterial cross-feeding can promote gene retention by lowering gene expression costs.

Ying-Chih Chuang, Megan G Behringer, Gillian Patton, Jordan T Bird, Crystal E Love, Ankur Dalia, James B McKinlay

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ying-Chih ChuangDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-3626-6631
Megan G BehringerDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0001-7036-6014
Gillian PattonDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.ORCID 0009-0001-7367-4132
Jordan T BirdBattelle Memorial Institute, Columbus, OH 43201.ORCID 0000-0001-5753-6058
Crystal E LoveDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0001-9988-7067
Ankur DaliaDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0003-2203-1230
James B McKinlayDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0003-2401-6229

Funding

Mechanisms and regulation of horizontal gene transfer by natural transformation in Vibrio choleraeR35GM128674 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Ankur Dalia · 2018 to 2026
$3.8M
Using Experimental Evolution to Evaluate Environmental Effects on Microbial Mutation and AdaptationR35GM150625 · NIGMS · VANDERBILT UNIVERSITY · PI Megan Grace Behringer · 2023 to 2026
$1.8M
NIGMS NIH HHS R35 GM128674NIGMS NIH HHS R35 GM150625
6 · The paper itself

Abstract

Gene loss is expected in microbial communities when the benefit of obtaining a biosynthetic precursor from a neighbor via cross-feeding outweighs the cost of retaining a biosynthetic gene. However, gene cost primarily comes from expression, and many biosynthetic genes are only expressed when needed. Thus, one can conversely expect cross-feeding to repress biosynthetic gene expression and promote gene retention by lowering gene cost. Here we examined long-term bacterial cocultures pairing

Indexed as

adenineBlack Queen Hypothesiscross-feedingexcretiongene lossmicrobial interactionsmicrobial physiologymutualismpalustrispurineRhodopseudomonassiderophore

Identifiers

PMID39229193
PMCPMC11370488

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.