Evidence map›Paper›PMID 39229096›Full record

ArticlebioRxiv : the preprint server for biology2024

The Clonal Hematopoiesis-associated Gene

Terrence N Wong, Anna Mychalowych, Ellie R Feldpausch, Alexander Carson, Darja Karpova, Daniel C Link

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Terrence N WongDivision of Hematology-Oncology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-4509-208X
Anna MychalowychDivision of Hematology-Oncology, University of Michigan, Ann Arbor, Michigan.
Ellie R FeldpauschDivision of Hematology-Oncology, University of Michigan, Ann Arbor, Michigan.
Alexander CarsonDivision of Hematology-Oncology, University of Michigan, Ann Arbor, Michigan.
Darja KarpovaDivision of Oncology, Washington University School of Medicine, St. Louis, Missouri.
Daniel C LinkDivision of Oncology, Washington University School of Medicine, St. Louis, Missouri.

Funding

Specimen Acquistition and Expression ProfilingP01CA101937 · NCI · WASHINGTON UNIVERSITY · PI LINK, DANIEL C · 2003 to 2023
$58.8M
CLONAL EVOLUTION OF HEMATOPOIETIC STEM CELLS DURING CHEMOTHERAPY AND TRANSPLANTATIONK08CA197369 · NCI · WASHINGTON UNIVERSITY · PI WONG, TERRENCE NEAL · 2016 to 2020
$607k
NCI NIH HHS K08 CA197369NCI NIH HHS P01 CA101937
6 · The paper itself

Abstract

Somatic mutations arising in hematopoietic stem cells (HSCs) may provide the latter with a fitness advantage, allowing the mutant HSC to clonally expand. Such mutations have been recurrently identified in the chromatin modifier,

Identifiers

PMID39229096
PMCPMC11370474

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.