Evidence map›Paper›PMID 39229007›Full record

ArticlebioRxiv : the preprint server for biology2025

The role of innate immunity, antibiotics, and bacteriophages in the course of bacterial infections and their treatment.

Brandon A Berryhill, Teresa Gil-Gil, Christopher Witzany, David A Goldberg, Nic M Vega, Roland R Regoes, Bruce R Levin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Brandon A BerryhillDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-3430-0901
Teresa Gil-GilDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-0136-3965
Christopher WitzanyInstitute of Integrative Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-7128-6419
David A GoldbergDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.
Nic M VegaDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0002-9929-6109
Roland R RegoesInstitute of Integrative Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0001-8319-5293
Bruce R LevinDepartment of Biology, Emory University; Atlanta, Georgia, 30322, USA.ORCID 0000-0003-3600-2780

Funding

Theoretical and Experimental Studies of the Population and Evolutionary Dynamics of Bacteria and Bacteriophage.R35GM136407 · NIGMS · EMORY UNIVERSITY · PI LEVIN, BRUCE RICHARD · 2020 to 2024
$2.0M
NIGMS NIH HHS R35 GM136407
6 · The paper itself

Abstract

Critical to our understanding of infections and their treatment is the role the innate immune system plays in controlling bacterial pathogens. Nevertheless, many in vivo systems are made or modified such that they do not have an innate immune response. Use of these systems denies the opportunity to examine the synergy between the immune system and antimicrobial agents. In this study we demonstrate that the larva of

Indexed as

antibiotic resistanceantibioticsbacteriophagesGalleria mellonellainfection dynamicsinnate immunitymodel systemStaphylococcus aureus

Identifiers

PMID39229007
PMCPMC11370618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.