Evidence map›Paper›PMID 39228659›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Post-Kidney Transplant Cancer: A Real-World Retrospective Analysis From a Single Italian Center.

Giulia Vanessa Re Sartò, Carlo Alfieri, Laura Cosmai, Emilietta Brigati, Mariarosaria Campise, Anna Regalia, Simona Verdesca, Paolo Molinari, Anna Maria Pisacreta, Marta Pirovano and 3 more

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giulia Vanessa Re Sartò *Nephrology and Dialysis Unit, ASST Fatebenefratelli Sacco, Milano, Italy.
Carlo Alfieri *Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Laura CosmaiNephrology and Dialysis Unit, ASST Fatebenefratelli Sacco, Milano, Italy.
Emilietta BrigatiDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Mariarosaria CampiseDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Anna RegaliaDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Simona VerdescaDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Paolo MolinariDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Anna Maria PisacretaDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Marta PirovanoNephrology and Dialysis Unit, ASST Fatebenefratelli Sacco, Milano, Italy.
Luca NardelliDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.
Maurizio GallieniNephrology and Dialysis Unit, ASST Fatebenefratelli Sacco, Milano, Italy.
Giuseppe CastellanoDepartment of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the epidemiology of cancer after kidney transplantation (KTx), investigating its risk factors and impact on therapeutic management and survival in KTx recipients (KTRs). The association between modification of immunosuppressive (IS) therapy after cancer and survival outcomes was analyzed. We collected data from 930 KTRs followed for 7 [1-19] years. The majority of KTRs received KTx from a deceased donor (84%). In total, 74% of patients received induction therapy with basiliximab and 26% with ATG. Maintenance therapy included steroids, calcineurin inhibitors, and mycophenolate. Patients with at least one cancer (CA+) amounted to 19%. NMSC was the most common tumor (55%). CA+ were older and had a higher BMI. Vasculitis and ADPKD were more prevalent in CA+. ATG was independently associated with CA+ and was related to earlier cancer development in survival and competing risk analyses (

Indexed as

Immunosuppressive AgentsKidney TransplantationNeoplasmsAdultAgedAntilymphocyte SerumBasiliximabFemaleHumansItalyMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsAntilymphocyte SerumBasiliximabImmunosuppressive Agentsimmunosuppressive therapyinduction therapykidney transplantmTOR inhibitorspost-kidney transplant cancer

Identifiers

PMID39228659
PMCPMC11368674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.