Evidence map›Paper›PMID 39228483›Full record

ReviewReviews in cardiovascular medicine2024

Atrial High-Rate Episodes and Subclinical Atrial Fibrillation: State of the Art and Clinical Questions with Complex Solutions.

Carola Griffith Brookles, Roberto De Ponti, Vincenzo Russo, Matteo Ziacchi, Gemma Pelargonio, Michela Casella, Maurelio Lauretti, Manola Vilotta, Sakis Themistoclakis, Antonio D'Onofrio and 3 more

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Editorial: Insights in cardiac rhythmology 2023.Frontiers in cardiovascular medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carola Griffith BrooklesCardiology Division, Department of Medical Sciences, "Città della Salute e della Scienza" Hospital, Univerisity of Turin, 10116 Turin, Italy.
Roberto De PontiDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Vincenzo RussoCardiology Unit, Department of Translational Medical Sciences, Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Matteo ZiacchiInstitute of Cardiology, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138 Bologna, Italy.
Gemma PelargonioFondazione Policlinico Universitario Agostino Gemelli IRCCS, University "Cattolica del Sacro Cuore", 00168 Rome, Italy.
Michela CasellaCardiology and Arrhythmology Clinic, Department of Clinical, Special and Dental Sciences, Marche Polytechnic University, Marche University Hospital, 60126 Ancona, Italy.
Maurelio LaurettiCardiology Division, "Vito Fazzi" Hospital, 73100 Lecce, Italy.
Manola VilottaDepartment of Heart and Vessels, Ospedale di Circolo, 21100 Varese, Italy.
Sakis ThemistoclakisDepartment of Cardiothoracic, Vascular Medicine and Intensive Care, Dell'Angelo Hospital, 30174 Mestre-Venice, Italy.
Antonio D'OnofrioElectrophysiology and Cardiac Pacing Unit, Cardiology Division, Monaldi Hospital, 80131 Naples, Italy.
Giuseppe BorianiCardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, 41124 Modena, Italy.
Matteo AnselminoCardiology Division, Department of Medical Sciences, "Città della Salute e della Scienza" Hospital, Univerisity of Turin, 10116 Turin, Italy.
AIAC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial high-rate episodes (AHREs) and subclinical atrial fibrillation (AF) are frequently registered in asymptomatic patients with cardiac implantable electronic devices (CIEDs) and insertable cardiac monitors (ICMs). While an increased risk of thromboembolic events (e.g., stroke) and benefits from anticoagulation have been widely assessed in the setting of clinical AF, concerns persist about optimal clinical management of subclinical AF/AHREs. As a matter of fact, an optimal threshold of subclinical episodes' duration to predict stroke risk is still lacking and recently published randomized clinical trials assessing the impact of anticoagulation on thromboembolic events in this specific setting have shown contrasting results. The aim of this review is to summarize current evidence regarding classification and clinical impact of subclinical AF/AHREs and to discuss the latest evidence regarding the potential benefit of anticoagulation in this setting, highlighting which clinical questions are still unanswered.

Indexed as

anticoagulationatrial high-rate episodecardiac implantable electronic devicescognitive impairmentsubclinical atrial fibrillationthromboembolic risk

Identifiers

PMID39228483
PMCPMC11366991

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.