ReviewFrontiers in microbiology2024
Oral microbiota and metabolites: key players in oral health and disorder, and microbiota-based therapies.
Review in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Application of double-sleeve endotracheal tube in infection control for icu patients: a randomized controlled trial.Head & face medicine · 2025Trial
- Microbiota and head and neck cancers: Mechanistic insights and translational potential.Virulence · 2026Review
- Exploring the Oral Resistome: From Metagenomics to Precision Oral Health.Microorganisms · 2026Review
- Oral Microbiota, the Oral-Brain Axis, and Neurodegeneration: Mechanisms and Dietary Modulation.Antioxidants (Basel, Switzerland) · 2026Review
- The oral microbiota in oral squamous cell carcinoma: unravelling mechanisms and clinical potential.Cancer cell international · 2026Review
- The Mechanism and Pathways of Formation and Modification of Salivary Metabolic Profile in Cancer.Current issues in molecular biology · 2026Review
- Ectopic Olfactory Receptors in Oral Health and Disease: Molecular Links Between Chemosensing, Tissue Repair, Inflammation, and Cancer.International journal of molecular sciences · 2026Review
- Interindividual differences in acidogenic potential of the salivary microbiome after mouthwash exposure.BMC microbiology · 2026Article
- Durumamide A Inhibits NLRP3 Assembly, Limiting Pro-Inflammatory Signaling in Human Gingival Fibroblasts.Journal of periodontal research · 2026Article
- Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations.International journal of molecular sciences · 2026Review
- Reconceptualizing gingival keratinization: from epithelial autonomy to artificial intelligence-driven therapeutic planning.Odontology · 2026Review
- The Role ofBiomedicines · 2026Review
- Influence of E-Liquids and Oral Commensal Bacteria on the Growth ofDentistry journal · 2026Article
- Polyphenolic nanodot-integrated spindle nanoplatform heals oral mucositis via microbiota restoration and glycolysis inhibition.Journal of nanobiotechnology · 2026Article
- The Oral Microbiome and Systemic Health: Current Insights into the Mouth-Body Connection.Life (Basel, Switzerland) · 2026Review
- Diet-Oral Microbiota Interactions and Salivary Biomarkers of Nutritional Health: A Narrative Review.Nutrients · 2026Review
- The biosynthetic gene cluster landscape of the oral microbiome across health and dental caries.Journal of industrial microbiology & biotechnology · 2026Article
- Salivary proteins, proteases, and disease pathophysiology in oral health and precision diagnostics: a narrative review.Frontiers in dental medicine · 2026Review
- Postbiotics and phage synergy in precision oral microbiome engineering: systems biology strategies targetingFrontiers in molecular biosciences · 2026Review
- Mapping the oral microbiome in children with oral diseases using next-generation sequencing: a systematic review.Journal of oral microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The review aimed to investigate the diversity of oral microbiota and its influencing factors, as well as the association of oral microbiota with oral health and the possible effects of dysbiosis and oral disorder. The oral cavity harbors a substantial microbial burden, which is particularly notable compared to other organs within the human body. In usual situations, the microbiota exists in a state of equilibrium; however, when this balance is disturbed, a multitude of complications arise. Dental caries, a prevalent issue in the oral cavity, is primarily caused by the colonization and activity of bacteria, particularly streptococci. Furthermore, this environment also houses other pathogenic bacteria that are associated with the onset of gingival, periapical, and periodontal diseases, as well as oral cancer. Various strategies have been employed to prevent, control, and treat these disorders. Recently, techniques utilizing microbiota, like probiotics, microbiota transplantation, and the replacement of oral pathogens, have caught the eye. This extensive examination seeks to offer a general view of the oral microbiota and their metabolites concerning oral health and disease, and also the resilience of the microbiota, and the techniques used for the prevention, control, and treatment of disorders in this specific area.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.