Evidence map›Paper›PMID 39228203›Full record

ArticleTurkish journal of obstetrics and gynecology2024

Association between Mir-499, Mir-27a, and Mir-146a polymorphisms and their susceptibility to recurrent spontaneous abortion;

Gholamreza Bahari, Mohsen Taheri, Mojgan Mokhtari, Mahdiyeh Moudi, Mahdi Majidpour, Hossein Shahraki Ghadimi

Abstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gholamreza BahariChildren and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.ORCID 0000-0003-2531-4236
Mohsen TaheriGenetics of Non-Communicable Disease Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.ORCID 0000-0002-1110-4417
Mojgan MokhtariDepartment of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4560-1702
Mahdiyeh MoudiDepartment of Medical Biotechnology, School of Medicine, Neyshabour University of Medical Sciences, Neyshabour, Razavi Khorasan Province, Iran.ORCID 0000-0002-4502-6015
Mahdi MajidpourClinical Immunology Research Center of Zahedan University of Medical Sciences, Zahedan, Iran.ORCID 0000-0002-3696-6953
Hossein Shahraki GhadimiDepartment of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.ORCID 0000-0002-4207-2075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Recurrent spontaneous abortion (RSA) is defined as two or more pregnancy losses before 24 gestational weeks, accounting for 1-3% of fertile couples. A vast majority of single-nucleotide polymorphisms (SNPs) in some Materials and Methods: SNP genotyping of miR-27a (rs895819), miR-499 (rs3746444), and miR-146a (rs2910164) was performed using polymerase chain reaction (PCR)-restriction fragment length polymorphism and tetra amplification-refractory mutation system PCR in 98 patients with RSA and 105 healthy subjects. Results: Our results showed that the miR-499 rs3746444 and miR-27a rs895819 polymorphisms were significantly associated with RSA risk, whereas no significant differences were observed between the rs2910164 polymorphism and RSA susceptibility. Conclusion: We proposed that the miR-499 rs3746444 and miR-27a rs895819 polymorphisms were correlated with RSA in our population, but the miR-146a rs2910164 variant was not associated with the risk of RSA.

Indexed as

miR-146a rs2910164miR-27a rs895819MiR-499 rs3746444RSA risk

Identifiers

PMID39228203
PMCPMC11589323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.