Evidence map›Paper›PMID 39228197›Full record

ReviewAnnals of coloproctology2024

Tissue engineering and regenerative medicine approaches in colorectal surgery.

Bigyan B Mainali, James J Yoo, Mitchell R Ladd

Abstract readReview
In one paragraph

Review in Annals of coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bigyan B MainaliDepartment of General Surgery, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA.
James J YooWake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA.
Mitchell R LaddDepartment of General Surgery, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA.

Funding

CTSA K12 Program at Wake ForestK12TR004931 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicholette D. Allred · 2024 to 2026
$2.3M
NCATS NIH HHS K12 TR004931NIH HHS K12TR004931
6 · The paper itself

Abstract

Tissue engineering and regenerative medicine (TERM) is an emerging field that has provided new therapeutic opportunities by delivering innovative solutions. The development of nontraditional therapies for previously unsolvable diseases and conditions has brought hope and excitement to countless individuals globally. Many regenerative medicine therapies have been developed and delivered to patients clinically. The technology platforms developed in regenerative medicine have been expanded to various medical areas; however, their applications in colorectal surgery remain limited. Applying TERM technologies to engineer biological tissue and organ substitutes may address the current therapeutic challenges and overcome some complications in colorectal surgery, such as inflammatory bowel diseases, short bowel syndrome, and diseases of motility and neuromuscular function. This review provides a comprehensive overview of TERM applications in colorectal surgery, highlighting the current state of the art, including preclinical and clinical studies, current challenges, and future perspectives. This article synthesizes the latest findings, providing a valuable resource for clinicians and researchers aiming to integrate TERM into colorectal surgical practice.

Indexed as

Colorectal surgeryRegenerative medicineTissue engineering

Identifiers

PMID39228197
PMCPMC11375227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.