Evidence map›Paper›PMID 39227880›Full record

Trial reportBMC complementary medicine and therapies2024

Effectiveness and safety of acupuncture as an adjunctive therapy for chronic obstructive pulmonary disease: a randomised controlled trial.

Guixing Xu, Qin Luo, Mingsheng Sun, Liuyang Huang, Jiali Liu, Chunyan Yang, Qingsong Huang, Chan Xiong, Zuoqin Yang, Sha Yang and 2 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guixing XuAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Qin LuoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Mingsheng SunAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Liuyang HuangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Jiali LiuChinese Evidence-Based Medicine Center and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Chunyan YangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Qingsong HuangAffiliated Hospital of Chengdu University of Traditional Chinese Medicine, (Sichuan Hospital of Traditional Chinese Medicine), Chengdu, Sichuan, China.
Chan XiongChengdu Pidu District Hospital of Traditional Chinese Medicine, Department of Respiratory Medicine, Chengdu, Sichuan, China.
Zuoqin YangChengdu Pidu District Hospital of Traditional Chinese Medicine, Department of Acupuncture and Moxibustion, Chengdu, Sichuan, China.
Sha YangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China.
Fang ZengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China. zeng_fang@126.com.
Fanrong LiangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine Chinese Medicine, Chengdu, Sichuan, China. acuresearch@126.com.

Funding

Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine ZYYCXTD-D-202003Sichuan Provincial Nature Foundation 2022NSFSC1493
6 · The paper itself

Abstract

backgroundThe effectiveness and safety of acupuncture therapy to delay lung function decline in chronic obstructive pulmonary disease (COPD) remain unclear. This study aimed to determine whether acupuncture, as an adjunctive therapy to COPD-guided medication, could prevent lung function decline.

methodsThis randomised, two-centre study was conducted between February 2022 and July 2023. Men and women aged 40-80 years with COPD were recruited. Participants received active or sham acupuncture three times a week (36 sessions total). The primary outcome was the change in the percentage of forced expiratory volume for 1 s to the predicted value (FEV1%) between the baseline and after the intervention.

resultsOverall, 238 participants were screened, and 74 (58 men [78.4%]; mean [standard deviation] age, 69.6 [7.2] years) were randomised into the acupuncture and sham acupuncture groups (37 per group). After the intervention, the change in FEV1% was 1.35 (95% confidence interval [CI]: -0.47 to 3.17) and -2.44 (95% CI: -4.56 to -0.33) in the acupuncture and sham acupuncture groups, respectively. The difference was -3.97 (95% CI: -6.2 to -1.74), and the adjusted difference was -3.46 (95% CI: -5.69 to -1.24, P = 0.003) between the groups. A significantly less decline was found in forced expiratory volume for 1 s in the acupuncture group. All treatment-related adverse events (acupuncture = 11, sham = 2) were mild.

conclusionsCompared with sham acupuncture, acupuncture plus medication may delay lung function decline. However, further studies with a larger sample size and longer-term follow-up are needed to clarify the effects.

Indexed as

Acupuncture TherapyPulmonary Disease, Chronic ObstructiveAdultAgedAged, 80 and overFemaleForced Expiratory VolumeHumansMaleMiddle AgedTreatment OutcomeAcupuncture therapyChronic obstructiveForced expiratory volumeLungPulmonary disease

Identifiers

PMID39227880
PMCPMC11370288

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.