Evidence map›Paper›PMID 39227735›Full record

ArticleScientific reports2024

The impact of intracytoplasmic sperm injection versus conventional in vitro fertilization on the reproductive outcomes of couples with non-male factor infertility and frozen-thawed embryo transfer cycles.

Yuchao Zhang, Wen Zhang, Yanli Liu, Bingnan Ren, Yichun Guan

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuchao Zhang *Department of Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Zhengzhou, 450052, Henan, China. yuchao1988@yeah.net.
Wen Zhang *Department of Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Zhengzhou, 450052, Henan, China.
Yanli LiuDepartment of Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Zhengzhou, 450052, Henan, China.
Bingnan RenDepartment of Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Zhengzhou, 450052, Henan, China.
Yichun GuanDepartment of Reproductive Medicine, The Third Affiliated Hospital of Zhengzhou University, No.7 Kangfuqian Street, Erqi, Zhengzhou, 450052, Henan, China. lisamayguan@163.com.

Funding

Joint Construction Project of Henan Medical Science and Technology Research Plan LHGJ20190400Joint Construction Project of Henan Medical Science and Technology Research Plan LHGJ20200435National Key R&D Program "Fertility Health and Health Security for Women and Children" 2021YFC2700602
6 · The paper itself

Abstract

This study was aimed to investigate the impact of intracytoplasmic sperm injection (ICSI) on reproductive outcomes in couples with non-male factor infertility and frozen-thawed embryo transfer (FET) treatment. This retrospective cohort study involved a total of 10,143 cycles from 6206 couples who underwent FET at the Third Affiliated Hospital of Zhengzhou University between January 2016 and September 2022. Patients were categorized into two groups based on the insemination methods of transferred embryos. Clinical and neonatal outcomes were compared between ICSI and conventional in vitro fertilization (cIVF) groups. The results showed that ICSI was not associated with improved clinical outcomes compared to cIVF. However, ICSI was associated with lower birthweight when twins were born. In conclusion, although subgroup analysis showed that ICSI was associated with slightly improved live birth rate for infertile couples with non-male factor infertility compared to cIVF, the regression analysis showed that ICSI did not demonstrate any improvement of the reproductive outcomes. The infertile women with twin pregnancies should be further informed of the lower birthweight and lower birth length when their oocytes were inseminated with ICSI. The findings of this study provide valuable insights for clinicians when discussing the benefits and risks of ICSI in patients with non-male factor infertility.

Indexed as

Embryo TransferFertilization in VitroSperm Injections, IntracytoplasmicAdultCryopreservationFemaleHumansInfertility, FemaleMalePregnancyPregnancy OutcomePregnancy RateRetrospective StudiesFrozen-thawed embryo transferIntracytoplasmic sperm injectionNon-male factor infertilityPreterm birthReproductive outcome

Identifiers

PMID39227735
PMCPMC11372061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.