Evidence map›Paper›PMID 39227724›Full record

ArticleScientific reports2024

How carbon sources drive cellulose synthesis in two Komagataeibacter xylinus strains.

Federico Lasagni, Stefano Cassanelli, Maria Gullo

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. The Effect ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Federico LasagniDepartment of Life Sciences, University of Modena and Reggio Emilia, Reggio Emilia, Italy.
Stefano CassanelliDepartment of Life Sciences, University of Modena and Reggio Emilia, Reggio Emilia, Italy. stefano.cassanelli@unimore.it.
Maria GulloDepartment of Life Sciences, University of Modena and Reggio Emilia, Reggio Emilia, Italy. maria.gullo@unimore.it.

Funding

NextGenerationEU IR0000005Next generationEU - PRIN 2022 20228Z34PF
6 · The paper itself

Abstract

Bacterial cellulose synthesis from defined media and waste products has attracted increasing interest in the circular economy context for sustainable productions. In this study, a glucose dehydrogenase-deficient Δgdh K2G30 strain of Komagataeibacter xylinus was obtained from the parental wild type through homologous recombination. Both strains were grown in defined substrates and cheese whey as an agri-food waste to assess the effect of gene silencing on bacterial cellulose synthesis and carbon source metabolism. Wild type K2G30 boasted higher bacterial cellulose yields when grown in ethanol-based medium and cheese whey, although showing an overall higher D-gluconic acid synthesis. Conversely, the mutant Δgdh strain preferred D-fructose, D-mannitol, and glycerol to boost bacterial cellulose production, while displaying higher substrate consumption rates and a lower D-gluconic acid synthesis. This study provides an in-depth investigation of two K. xylinus strains, unravelling their suitability for scale-up BC production.

Indexed as

CarbonCelluloseAcetobacteraceaeGluconatesGlycerolMannitolCarbonCelluloseGluconatesgluconic acidGlycerolMannitolAgro-wastesBacterial celluloseGluconic acidGlucose dehydrogenaseKomagataeibacter xylinus

Identifiers

PMID39227724
PMCPMC11371920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.