Evidence map›Paper›PMID 39227473›Full record

ArticleAesthetic plastic surgery2025

Precise Needle and Cannula Placement in the Forehead During Aesthetic Procedures: Can Device and Angulation Influence Accuracy? A Fresh Frozen Specimen Study.

Gladstone Eustaquio de Lima Faria, Alexander D Nassif, Rebecca Ignacio Subirá Medina, Sheila Espicalsky, Luciana Zattar, Ricardo Frota Boggio

Abstract read
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gladstone Eustaquio de Lima FariaInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil. gladstonefaria@hotmail.com.ORCID 0000-0002-0754-2019
Alexander D NassifInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil.ORCID 0000-0003-3969-9480
Rebecca Ignacio Subirá MedinaInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil.ORCID 0000-0001-6756-4263
Sheila EspicalskyInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil.
Luciana ZattarInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil.ORCID 0000-0002-5229-8596
Ricardo Frota BoggioInstituto Boggio - Medicina, ensino e pesquisa, Rua Cincinato Braga, 37, 8°Andar, Bela Vista, SP, 04004-030, Brazil.ORCID 0000-0002-5139-0243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMyomodulation is a technique aimed at enhancing the dynamics of muscle contraction and relaxation through methods like hyaluronic acid (HA) injection. Achieving optimal outcomes depends on the precise placement of the injected product within the targeted anatomical plane. This is particularly important in the forehead, an area with elevated vascular risk. The selected treatment techniques must ensure both efficacy and safety. This study aims to assess the anatomical precision of HA injections in the forehead using different techniques and devices.

methodsFour fresh frozen specimens were injected with HA by five experienced board-certified plastic surgeons using three different techniques/devices: (1) a 50 mm, 22G microcannula; (2) a 13 mm, 27G needle with the bevel down at a 45-degree angle; and (3) the same needle positioned at a 90-degree angle. Ultrasound analysis was used to evaluate the precision of each approach.

resultsBoth the cannula technique and the needle technique with the bevel down at a 45-degree angle consistently delivered the filler to the supraperiosteal layer in 100% of cases without spreading. However, the 90-degree needle technique, despite correct placement on the periosteum, resulted in filler dispersion across multiple layers.

conclusionThe accuracy of filler placement in the forehead is influenced by the choice of device and its angulation. It is recommended to use a cannula with the entry point at the frontalis crest or a needle angled at 45 degrees to the skin. The use of a needle at a 90-degree angle should be avoided to ensure precise placement and avoid filler migration. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .

Indexed as

CannulaCosmetic TechniquesDermal FillersForeheadHyaluronic AcidNeedlesCadaverEstheticsFemaleHumansMaleDermal FillersHyaluronic AcidAnatomyFillersForeheadHyaluronic acidSafety

Identifiers

PMID39227473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.