Evidence map›Paper›PMID 39226531›Full record

ReviewJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2024

Photodynamic therapy in dermatology: established and new indications.

Galina Balakirski, Percy Lehmann, Rolf-Markus Szeimies, Silke C Hofmann

Abstract readReview
In one paragraph

Review in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions for Bowen's disease: A systematic review and network meta-analysis of randomized controlled trials.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Photodynamic Therapy in Dermatology.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Current Perspectives on Photodynamic Therapy for Skin Diseases: A Narrative Review.Clinical, cosmetic and investigational dermatology · 2026
    Review
  9. Red light (630 nm) combined with low-dose ALA-PDT: a novel strategy for collagen remodeling and anti-aging efficacy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  10. Article
  11. Review
  12. Advancements and emerging trends in photodynamic therapy: innovations in cancer treatment and beyond.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  13. [Progress on carboxyl-substituted phthalocyanine photosen-sitizers and their drug delivery systems for photodynamic therapy].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  14. Photodynamic therapy in dermatology: established and new indications.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Galina BalakirskiCenter for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.ORCID 0000-0002-6093-9832
Percy Lehmann *Center for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.
Rolf-Markus SzeimiesDepartment of Dermatology and Allergology, Klinikum Vest GmbH, Recklinghausen, Academic Teaching Hospital of Ruhr University Bochum, Recklinghausen, Germany.
Silke C HofmannCenter for Dermatology, Allergology and Dermatosurgery, Helios University Hospital Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.ORCID 0000-0002-4221-386X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) is internationally established as an approved treatment option for in situ forms of keratinocytic skin cancer (actinic keratoses, Bowen's disease, basal cell carcinoma). For these indications, there are standardized treatment protocols using narrow-spectrum light sources or (artificial) daylight, the use of which is associated with successful healing, a low rate of lesion recurrence, and a very good cosmetic result. Daylight PDT is superior to conventional PDT in terms of significantly less pain and associated higher patient acceptance. Newer indications, for which no approval has yet been granted, but which nevertheless have sufficient evidence of efficacy according to the study situation, are inflammatory (lichen sclerosus, acne) and infectious dermatoses (viral warts, cutaneous leishmaniasis, atypical mycobacteriosis). In addition, PDT is increasingly being used in aesthetic dermatology with the aim of skin rejuvenation.

Indexed as

DermatologyPhotochemotherapyEvidence-Based MedicineHumansPhotosensitizing AgentsSkin DiseasesSkin NeoplasmsPhotosensitizing Agentsactinic keratosisbowen's diseasephotosensitizerred lightviral warts

Identifiers

PMID39226531
PMCPMC11626226

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.