Evidence map›Paper›PMID 39226382›Full record

ArticleCirculation2024

Angiotensin-(1-9) Retro-Enantiomer Peptide With Cardioprotective Activity.

Yvo Flores, Gerald Zapata-Torres, Agustín Nuñez, Douglas J Matthies, Larissa Alemán, Carolina Hernández-Fuentes, Gina Sánchez, Eyleen Araya, Fanny Guzman, Zully Pedrozo and 13 more

Abstract readLetter
In one paragraph

Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. New possibilities for protective arms by changing the structure of angiotensin (1-9).Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Yvo Flores *Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Gerald Zapata-Torres *Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Agustín NuñezAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Douglas J MatthiesFacultad Ciencias Químicas y Farmacéuticas (G.Z.-T., D.J.M.), Universidad de Chile, Santiago.ORCID 0000-0002-7673-4081
Larissa AlemánAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Carolina Hernández-FuentesAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Gina SánchezInstituto de Ciencias Biomédicas (ICBM), Facultad Medicina (G.S., Z.P., S.L.), Universidad de Chile, Santiago.
Eyleen ArayaDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Santiago, Chile (E.A.).
Fanny GuzmanNúcleo de Biotecnología de Curauma (NBC), Pontificia Universidad Católica de Valparaíso, Chile (F.G.).
Zully PedrozoAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Salvador GuardiolaInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.).ORCID 0000-0003-2644-1659
Mónica VareseInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.).ORCID 0000-0003-3179-079X
Ernest GiraltInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.).
Ivan MaslovDepartment of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC.ORCID 0000-0002-2322-3819
Mark Del BorgoDepartment of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC.ORCID 0000-0003-3724-9814
Robert E WiddopDepartment of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC.ORCID 0000-0002-6515-0435
Silvana ValdebenitoAustralia. Department of Neurobiology, University of Texas Medical Branch (UTMB), Galveston (S.V., E.A.E.).ORCID 0000-0002-6318-632X
Eliseo A EugeninAustralia. Department of Neurobiology, University of Texas Medical Branch (UTMB), Galveston (S.V., E.A.E.).ORCID 0000-0002-2925-4720
Mario ChiongAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).ORCID 0000-0002-5174-6545
Joseph A HillDepartment of Internal Medicine (Cardiology Division) (J.A.H., S.L.), University of Texas Southwestern Medical Center, Dallas.ORCID 0000-0002-5379-1614
María Paz OcaranzaAdvanced Center for Chronic Diseases (ACCDiS), Facultad Medicina, Pontificia Universidad Católica de Chile, Santiago (M.P.O.).
Marcelo J KoganAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).
Sergio LavanderoAdvanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Químicas y Farmacéuticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biofísica y Bioinformática (CM2B2).ORCID 0000-0003-4258-1483

Funding

Cardiomyocyte bromodomain protein 4 (BRD4) in physiology and diseaseR01HL147933 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2020 to 2023
$2.5M
ETS2-dependent control in cardiomyocyte ischemia/reperfusion injuryR01HL164586 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GILLETTE, THOMAS G, HILL, JOSEPH A · 2022 to 2025
$2.5M
Molecular Mechanisms of HFpEF-associated Atrial FibrillationR01HL155765 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GILLETTE, THOMAS G, HILL, JOSEPH A · 2021 to 2024
$1.6M
Mechanisms of obesity-dependent alterations in cardiomyocyte metabolismR01HL128215 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2017 to 2020
$1.6M
Vevo F2 Ultrasound Imaging SystemS10OD034385 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2023 to 2023
$318k
Rodent Ultrasound Imaging SystemS10RR023729 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2009 to 2009
$290k
NCRR NIH HHS S10 RR023729NHLBI NIH HHS R01 HL128215NHLBI NIH HHS R01 HL147933NHLBI NIH HHS R01 HL155765NHLBI NIH HHS R01 HL164586NIH HHS S10 OD034385
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Peptide FragmentsAngiotensin IAnimalsCardiotonic AgentsHumansAngiotensin ICardiotonic AgentsPeptide Fragmentsangiotensin-(1-9)hypertensionhypertrophymolecular dynamics simulationrenin-angiotensin system

Identifiers

PMID39226382
PMCPMC11373884

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.