Evidence map›Paper›PMID 39226341›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A neural algorithm for computing bipartite matchings.

Sanjoy Dasgupta, Yaron Meirovitch, Xingyu Zheng, Inle Bush, Jeff W Lichtman, Saket Navlakha

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A neural algorithm for computing bipartite matchings.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sanjoy DasguptaComputer Science and Engineering Department, University of California San Diego, La Jolla, CA 92037.
Yaron MeirovitchDepartment of Molecular and Cell Biology and Center for Brain Science, Harvard University, Cambridge, MA 02138.
Xingyu ZhengSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.ORCID 0000-0003-4704-1072
Inle BushSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.ORCID 0000-0003-2612-6317
Jeff W LichtmanDepartment of Molecular and Cell Biology and Center for Brain Science, Harvard University, Cambridge, MA 02138.
Saket NavlakhaSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724.

Funding

CRCNS: Common algorithmic strategies used by the brain for labeling points in high-dimensional spaceR01DC017695 · NIDCD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI NAVLAKHA, SAKET · 2018 to 2020
$1.3M
NIDCD NIH HHS R01 DC017695Pew Charitable Trusts (PCT) Pew Biomedical Scholar
6 · The paper itself

Abstract

Finding optimal bipartite matchings-e.g., matching medical students to hospitals for residency, items to buyers in an auction, or papers to reviewers for peer review-is a fundamental combinatorial optimization problem. We found a distributed algorithm for computing matchings by studying the development of the neuromuscular circuit. The neuromuscular circuit can be viewed as a bipartite graph formed between motor neurons and muscle fibers. In newborn animals, neurons and fibers are densely connected, but after development, each fiber is typically matched (i.e., connected) to exactly one neuron. We cast this synaptic pruning process as a distributed matching (or assignment) algorithm, where motor neurons "compete" with each other to "win" muscle fibers. We show that this algorithm is simple to implement, theoretically sound, and effective in practice when evaluated on real-world bipartite matching problems. Thus, insights from the development of neural circuits can inform the design of algorithms for fundamental computational problems.

Indexed as

AlgorithmsMotor NeuronsAnimalsHumansModels, NeurologicalNeural Networks, Computerbipartite matchingcircuit developmentneural algorithmneural-inspired computingneuromuscular circuit

Identifiers

PMID39226341
PMCPMC11406297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.