Evidence map›Paper›PMID 39226178›Full record

ArticleThe British journal of radiology2024

Liquid nitrogen-based cryoablation: complication rates for lung, bone, and soft tissue tumors cryoablation.

Franco Orsi, Aida Shazlin Hamiddin, Caterina Sattin, Caterina Pizzi, Gianluca Maria Varano, Paolo Della Vigna, Giovanni Mauri, Daniele Maiettini, Guido Bonomo

Abstract read
In one paragraph

Article in The British journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Franco OrsiDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.ORCID 0000-0002-7330-0499
Aida Shazlin HamiddinDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.
Caterina SattinUniversità degli studi di Milano, Milan, 20122, Italy.ORCID 0000-0003-2311-6826
Caterina PizziUniversità degli studi di Milano, Milan, 20122, Italy.
Gianluca Maria VaranoDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.
Paolo Della VignaDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.
Giovanni MauriDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.
Daniele MaiettiniDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.
Guido BonomoDepartment of Interventional Radiology, Istituto Europeo di Oncologia (IRCCS), Milan, Via Giuseppe Ripamonti 435, Milan-20141, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to assess the complication rate during and 24 hours after cryoablation in lung, bone, and soft tissue tumors.

methodsWe reviewed complications in a total of 85 consecutive patients who underwent cryoablation using a liquid nitrogen-based system in various lesions between April 2017 and October 2022. There were no liver and renal lesions. Complications were categorized using the Society of Interventional Radiology classification.

resultsEighty-five patients were treated for 96 lesions in the bone (36.4%; 35 of 96), lung (18.8%; 18 of 96), and soft tissue (44.8%; 43 of 96). The primary technical success rate was 97.7% (83 of 85). The total grade 2 and 1 complication rates were 5.2% (5/96) and 20.8% (20/96), respectively. Two patients had asymptomatic pulmonary embolisms incidentally noted at the 24-hour follow-up computed tomography (grade 2). The most frequent complications were simple and hemorrhagic pleural effusions (18.7%; 18 of 96). Lung procedures had the highest complication rate, where 13 patients (72.2%; 13 of 18) reported complications, including 2 cases of symptomatic hydropneumothorax requiring drainage (grade 2) and an additional 2 days of hospital stay. Eight patients (24.2%; 8 of 33) with bone lesions and 4 (9.3%; 4 of 43) with soft tissue lesions experienced complications.

conclusionCryoablation using a liquid nitrogen-based system is safe, with only minor complications observed. ADVANCES IN KNOWLEDGE: This study provides data on the safety of liquid nitrogen-based percutaneous cryoablation in tumors located in lung, in bones and in soft tissues. Despite using larger diameter cryoprobes than those typically reported with argon-based system, our experience shows that complications are mostly low and comparable in frequency and severity.

Indexed as

Bone NeoplasmsCryosurgeryLung NeoplasmsNitrogenPostoperative ComplicationsSoft Tissue NeoplasmsAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedNitrogenCryoablationInterventional oncologyLiquid nitrogen

Identifiers

PMID39226178
PMCPMC11491613

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.