Evidence map›Paper›PMID 39226172›Full record

ArticleSTAR protocols2024

Protocol to investigate the gradual selection and deployment of goal-oriented search strategies during unsupervised navigation in mice.

Martina Parrini, Pico Caroni, Maria Spolidoro

Abstract read
In one paragraph

Article in STAR protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Martina ParriniFriedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland.
Pico CaroniFriedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland. Electronic address: caroni@fmi.ch.
Maria SpolidoroFriedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland. Electronic address: mariaspo@gmail.com.

Funding

The Effect of Nanoparticle Encapsulated Resveratrol on Treatment of PeriodontitisKL2TR001882 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Elizabeta Nemeth · 2016 to 2026
$13.1M
Caltech/UCLA Individualized Theranostic Engineering to Advance Metabolic System (iTEAM)T32EB027629 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Dino Di Carlo, Azita Emami · 2020 to 2026
$2.0M
A soft magnetoelastic microneedle patch for rapid skin cancer screeningR01CA287326 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jun Chen · 2024 to 2026
$1.1M
NCATS NIH HHS KL2 TR001882NCI NIH HHS R01 CA287326NIBIB NIH HHS T32 EB027629
6 · The paper itself

Abstract

The ability of rodents to effectively navigate in an environment is based on trial-and-error learning and flexible decision-making and can be analyzed via navigational trajectories. We present a protocol for studying the deployment of search strategies in mice using the Morris water maze. We describe steps for assigning mice to different maze variations and procedures for post-training tracking and analysis. This protocol represents an effective behavioral readout to probe brain networks involved in strategy deployment and goal-oriented behavior. For complete details on the use and execution of this protocol, please refer to Parrini et al.

Indexed as

GoalsMaze LearningAnimalsBehavior, AnimalMaleMiceSpatial Navigationbehaviorcognitive neuroscienceneuroscience

Identifiers

PMID39226172
PMCPMC11419921

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.