Evidence map›Paper›PMID 39225871›Full record

ArticleCurrent microbiology2024

Antifungal Potential and Mechanism of Bacillus velezensis HeN-7 Isolated from Tobacco Leaves on Bipolaris sorokiniana.

Xiaojie Lin, Jianwei Wang, Zhipeng Hou, Shiming Ren, Wenxiu Wang, Yanhui Yang, Yanjie Yi, Yanling Zhang, Ruifang Li

Abstract read
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In one paragraph

Article in Current microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Characterization ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Frontiers in cellular and infection microbiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaojie Lin *Zhengzhou Key Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, No. 100 Lianhua Street, Zhengzhou, 450001, Henan, People's Republic of China.
Jianwei Wang *Key Laboratory of Eco-Environment and Tobacco Leaf Quality, Zhengzhou Tobacco Research Institute of CNTC, No. 2 Fengyang Street, Zhengzhou, 450001, Henan, People's Republic of China.
Zhipeng HouCollege of Biological Engineering, Henan University of Technology, Zhengzhou, 450001, Henan, People's Republic of China.
Shiming RenCollege of Biological Engineering, Henan University of Technology, Zhengzhou, 450001, Henan, People's Republic of China.
Wenxiu WangCollege of Biological Engineering, Henan University of Technology, Zhengzhou, 450001, Henan, People's Republic of China.
Yanhui YangZhengzhou Key Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, No. 100 Lianhua Street, Zhengzhou, 450001, Henan, People's Republic of China.
Yanjie YiZhengzhou Key Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, No. 100 Lianhua Street, Zhengzhou, 450001, Henan, People's Republic of China. yiyanjie@haut.edu.cn.
Yanling ZhangKey Laboratory of Eco-Environment and Tobacco Leaf Quality, Zhengzhou Tobacco Research Institute of CNTC, No. 2 Fengyang Street, Zhengzhou, 450001, Henan, People's Republic of China. zhangyanling@ztri.com.cn.
Ruifang LiZhengzhou Key Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, No. 100 Lianhua Street, Zhengzhou, 450001, Henan, People's Republic of China. lrf@haut.edu.cn.ORCID http://orcid.org/0000-0002-4824-0930

Funding

Innovative Funds Plan of Henan University of Technology 2020ZKCJ23Key Research and Development Program of CNTC 110202102035Natural Science Foundation of Henan Province 2323000421165
6 · The paper itself

Abstract

Wheat leaf blight caused by Bipolaris sorokiniana is a widespread fungal disease that poses a serious risk to wheat. Biological control without causing environmental pollution is one of the safest and most effective method to control plant diseases. The antagonistic bacterial strain HeN-7 (identified as Bacillus velezensis) was isolated from tobacco leaves cultivated in Henan province, China. The results of different concentrations of cell-free supernatant (CFS) from HeN-7 culture against B. sorokiniana mycelia showed that 20% HeN-7 CFS (v/v) reached the maximum inhibition rate of 96%. In the potted plants control assay, B. velezensis HeN-7 CFS exhibited remarkable biocontrol activity on the wheat infected with B. sorokiniana, the best pot control efficacy was 65% at 20% CFS. The research on the mechanism of action demonstrated that HeN-7 CFS induced the membrane lipid peroxidation in B. sorokiniana, leading to the disruption of cell membrane integrity and resulting in the leakage of cell contents; in addition, the intracellular mitochondrial membrane potential in mycelium dissipated and reactive oxygen species accumulated, thereby inhibiting the growth of B. sorokiniana. These results indicate that B. velezensis HeN-7 is a promising candidate as a biological control agent against Bipolaris sorokiniana infection.

Indexed as

BacillusBipolarisNicotianaPlant DiseasesPlant LeavesAntibiosisAntifungal AgentsChinaMyceliumReactive Oxygen SpeciesTriticumAntifungal AgentsReactive Oxygen Species

Identifiers

PMID39225871

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.