Evidence map›Paper›PMID 39225387›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Simultaneously Controlling Inflammation and Infection by Smart Nanomedicine Responding to the Inflammatory Microenvironment.

Xinjing Lv, Jie Min, Jie Huang, Hairong Wang, Song Wei, Chenxiao Huang, Jianfeng Dai, Zhengrong Chen, Huiting Zhou, Yunyun Xu and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Review
  7. [Advancement in neutrophil-based drug delivery systems].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  8. Article
  9. Treatment of lung diseasesMaterials today. Bio · 2025
    Review
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinjing LvChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Jie MinChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Jie HuangChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Hairong WangChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Song WeiChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Chenxiao HuangInstitutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, Jiangsu, 215123, China.
Jianfeng DaiInstitutes of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, Jiangsu, 215123, China.
Zhengrong ChenChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Huiting ZhouChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Yunyun XuChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
He ZhaoChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.
Zhuang LiuInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu, 215123, China.ORCID 0000-0002-1629-1039
Jian WangChildren's Hospital of Soochow University, Pediatric Research Institute of Soochow University, Suzhou, Jiangsu, 215123, China.

Funding

'111' program from the Ministry of Education of ChinaCollaborative Innovation Center of Suzhou Nano Science and TechnologyGusu Talent Program GSWS2019015Gusu Talent Program GSWS2022061Jiangsu health commission project BE2023714Jiangsu health commission project M2022120National Key Research and Development Program of China 2021YFF0701800National Natural Science Foundation of China 21927803National Natural Science Foundation of China 52032008National Natural Science Foundation of China 81900495Suzhou science and technology project SKJY2023058
6 · The paper itself

Abstract

The overactivated immune cells in the infectious lesion may lead to irreversible organ damages under severe infections. However, clinically used immunosuppressive anti-inflammatory drugs will usually disturb immune homeostasis and conversely increase the risk of infections. Regulating the balance between anti-inflammation and anti-infection is thus critical in treating certain infectious diseases. Herein, considering that hydrogen peroxide (H

Indexed as

InflammationNanomedicineNanoparticlesAnimalsChlorophyllidesDisease Models, AnimalHumansHydrogen PeroxideMicePhotosensitizing AgentsPolylactic Acid-Polyglycolic Acid CopolymerPorphyrinsChlorophyllidesHydrogen PeroxidePhotosensitizing AgentsphytochlorinPolylactic Acid-Polyglycolic Acid CopolymerPorphyrinsanti‐infection and anti‐inflammation treatmentbioluminescence resonance energy transferinflammatory microenvironmentmyeloperoxidaseneutrophils

Identifiers

PMID39225387
PMCPMC11497003

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.