Evidence map›Paper›PMID 39225340›Full record

ArticlePsychosomatic medicine

Ecologically Assessed Sleep Duration and Arterial Stiffness in Healthy Men and Women.

Allison E Gaffey, Kristie M Walenczyk, Joseph E Schwartz, Martica H Hall, Matthew M Burg

Abstract read
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Research progress in central aortic pressure estimation algorithms].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Allison E GaffeyFrom the Department of Internal Medicine (Cardiovascular Medicine) (Gaffey, Walenczyk, Burg), Yale School of Medicine, New Haven; VA Connecticut Healthcare System (Gaffey, Walenczyk, Burg), West Haven, Connecticut; Department of Psychiatry and Behavioral Health (Schwartz), Renaissance School of Medicine, Stony Brook; Department of Medicine (Schwartz), Columbia University Irving Medical Center, New York, New York; Department of Psychiatry (posthumously) (Hall), University of Pittsburgh, Pittsburgh, Pennsylvania; and Department of Anesthesiology (Burg), Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0002-2960-2772
Kristie M WalenczykORCID 0000-0003-3378-7017
Joseph E SchwartzORCID 0000-0002-8944-3566

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Stress, Sleep, and Arterial StiffnessR01HL126770 · NHLBI · YALE UNIVERSITY · PI BURG, MATTHEW M · 2016 to 2019
$3.3M
PTSD, Sleep, and Risk for Incident HypertensionR01HL125587 · NHLBI · YALE UNIVERSITY · PI BURG, MATTHEW M · 2015 to 2018
$3.2M
Social Vulnerability, Sleep, and Early Hypertension Risk in Younger AdultsK23HL168233 · NHLBI · YALE UNIVERSITY · PI Allison Gaffey · 2023 to 2026
$517k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL168233NHLBI NIH HHS R01 HL125587NHLBI NIH HHS R01 HL126770
6 · The paper itself

Abstract

objectiveAmong younger adults, to determine the associations of actigraph- and self-reported sleep duration with arterial stiffness (AS) assessed in clinic and in ecologically valid contexts, and to examine sex-specific associations.

methodsHealthy adults ( n = 282, median age = 29 years, 67% women) completed a state-of-the-art assessment of AS at rest (SphygmoCor; carotid femoral pulse wave velocity [cfPWV]; central augmentation index [cAIx]) and 7 days of actigraphy-assessed sleep with concurrent, momentary cAIx assessment for 36 hours (Oscar-2). Multivariable regressions were conducted on the full sample and sex-stratified to examine cross-sectional linear and quadratic associations of average sleep duration with resting PWV and cAIx, average cAIx while awake and asleep, and nocturnal cAIx dipping, adjusted for demographic and health covariates. Exploratory analyses included self-reported sleep duration with AS, and actigraphy and self-reported sleep duration with the ambulatory arterial stiffness index (AASI; Oscar-2).

resultsOverall and by sex, associations of average sleep duration with resting cfPWV, resting cAIx, and awake cAIx were not significant. Sleep duration showed a positive, linear association with sleep cAIx in women (95% confidence interval =1.07 to 5.86, Δ R2 = 0.021). Among women, sleep duration was also inversely associated with cAIx dipping (95% confidence interval = -4.48 to -0.95, Δ R2 = 0.020). Analyses with self-reported sleep duration and AASI as alternate predictors and outcomes were not significant.

conclusionsCertain sleep duration-AS associations may be sex-specific. Assessing sleep and momentary AS in ecologically valid conditions outside the research laboratory is valuable to understand these relations. Although this investigation should be replicated, findings raise the question of whether interventions to target sleep duration also reduce AS.

Indexed as

ActigraphySleepVascular StiffnessAdultCross-Sectional StudiesEcological Momentary AssessmentFemaleHumansMaleMiddle AgedPulse Wave AnalysisSelf ReportSex FactorsSleep DurationTime FactorsYoung Adult

Identifiers

PMID39225340
PMCPMC11560491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.