Evidence map›Paper›PMID 39225201›Full record

ReviewRecent patents on nanotechnology2025

Nano-Rutin: A Promising Solution for Alleviating Various Disorders.

Gunjan Nautiyal, Neha Minocha, Shiv Kant Sharma, Kiran Yadav, Dhirender Kaushik, Parijat Pandey

Abstract readReview
PubMed Publisher
In one paragraph

Review in Recent patents on nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gunjan NautiyalDepartment of Pharmaceutical Sciences, Gurugram University, Gurugram, 122018, Haryana, India.ORCID 0009-0009-8754-5989
Neha MinochaAmity Institute of Pharmacy, Amity University, Gurugram, 122413, Haryana, India.ORCID 0000-0002-0870-4972
Shiv Kant SharmaDepartment of Pharmaceutical Sciences, Gurugram University, Gurugram, 122018, Haryana, India.
Kiran YadavDepartment of Pharmaceutical Sciences, Chandigarh College of Pharmacy, CGC, Landran, Mohali, 140307, Punjab, India.
Dhirender KaushikDepartment of Pharmaceutical Sciences, Gurugram University, Gurugram, 122018, Haryana, India.ORCID 0000-0003-1217-9653
Parijat PandeyDepartment of Pharmaceutical Sciences, Gurugram University, Gurugram, 122018, Haryana, India.ORCID 0000-0003-2298-3645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRutin, often known as vitamin P, is a natural flavonoid compound, which offers a broad spectrum of therapeutic potentials. Rutin is metabolised to different compounds by the gut bacteria after consumption, therefore, very little is absorbed. Higher plants contribute to rutin synthesis in large quantities, and it may also be found in many fruits and fruity rinds, particularly citrus fruits and berries.

objectiveThe present paper highlights several studies and patents conducted on rutin along with its nanoformulations regarding its broad spectrum of therapeutic potentials.

methodsNumerous electronic databases, including Springer, PubMed, Science Direct, Pubchem, Google Patents etc. were searched to extract relevant published literature demonstrating rutin effectiveness in various ailments.

resultsThe reviewed literature showed that rutin and related flavonoids possess a variety of physiological properties that protects human beings, plants and animals. Antioxidant, anti-inflammatory, anti-allergic, cytoprotective, vasoprotective, anticarcinogenic, neuroprotective, cardioprotective, antibacterial, antiviral, antiprotozoal, antitumor, anti-hypertensive antiplatelet, antispasmodic and hypolipidemic, activities. Nanotechnology has been implemented for the improvement of the bioavailability of rutin using novel drug-delivery carriers.

conclusionThe study concludes that the development of rutin nanoformulations for multiple therapeutic approaches contributes towards enhanced aqueous solubility as well as tailored pharmacokinetics compared to conventional delivery of rutin. However, more investigations should be conducted to confirm the improved bioavailability of the rutin nanoformulations.

Indexed as

NanoparticlesRutinAnimalsAntioxidantsHumansPatents as TopicAntioxidantsRutinanti-inflammatoryantioxidantaqueous solubility.flavonoidnanoformulationsRutin

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.