Evidence map›Paper›PMID 39225008›Full record

ReviewAsian journal of andrology2025

Epigenetics of nonobstructive azoospermia.

Sezgin Gunes, Asli Metin Mahmutoglu, Neslihan Hekim

Abstract readReview
In one paragraph

Review in Asian journal of andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sezgin GunesDepartment of Medical Biology, Medical Faculty, Ondokuz Mayis University, Samsun 55139, Türkiye.
Asli Metin MahmutogluDepartment of Medical Biology, Medical Faculty, Yozgat Bozok University, Yozgat 66100, Türkiye.
Neslihan HekimDepartment of Medical Biology, Medical Faculty, Ondokuz Mayis University, Samsun 55139, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractNonobstructive azoospermia (NOA) is a severe and heterogeneous form of male factor infertility caused by dysfunction of spermatogenesis. Although various factors are well defined in the disruption of spermatogenesis, not all aspects due to the heterogeneity of the disorder have been determined yet. In this review, we focus on the recent findings and summarize the current data on epigenetic mechanisms such as DNA methylation and different metabolites produced during methylation and demethylation and various types of small noncoding RNAs involved in the pathogenesis of different groups of NOA.

Indexed as

AzoospermiaEpigenesis, GeneticDNA MethylationHumansMaleRNA, Small UntranslatedSpermatogenesisRNA, Small UntranslatedDNA methylationepigeneticshistone modificationsnoncoding RNAsnonobstructive azoospermia

Identifiers

PMID39225008
PMCPMC12112928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.