ArticleFrontiers in neurology2024
Exploring the genetic causal relationship between physical activity and migraine in European population based on Mendelian randomization analysis.
Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Associations of sleep, sedentary behavior, and physical activity with incident migraine: a prospective cohort study.BMC public health · 2026Article
- From trigeminal ganglion to cortex: ATG7 emerges as a key integrator of migraine pathways via multi-omics profiling.The journal of headache and pain · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Background: Previous studies have shown a connection between physical activity and migraines, but they don't prove a cause-and-effect relationship due to potential biases in observational methods. Methods: Utilizing accelerometer-measured physical activity data from a cohort of 377,234 participants in the UK Biobank and information from 599,356 European migraine patients (including 48,975 cases and 550,381 controls) obtained from 24 cohorts, we performed a bidirectional Mendelian randomization analysis to investigate the genetic bidirectional causal relationship between accelerometer-measured physical activity and migraines. Results: Research findings indicated a slight negative genetic correlation between "average acceleration" physical activity ( Conclusion: The Mendelian randomization results based on genetic data do not provide support for a causal association between physical activity and migraine.
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