Evidence map›Paper›PMID 39224857›Full record

ArticleProceedings of machine learning research2024

Retrieving Evidence from EHRs with LLMs: Possibilities and Challenges.

Hiba Ahsan, Denis Jered McInerney, Jisoo Kim, Christopher Potter, Geoffrey Young, Silvio Amir, Byron C Wallace

Abstract read
In one paragraph

Article in Proceedings of machine learning research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Cardiology-Chat: A Multi-LLMs Powered System for Cardiac Diagnostic Reasoning and Clinical Support.IEEE journal of translational engineering in health and medicine · 2026
    Article
  6. Evaluation of Large Language Models as Emergency Department Revisit Predictors.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. GraphCheck: Breaking Long-Term Text Barriers with Extracted Knowledge Graph-Powered Fact-Checking.Proceedings of the conference. Association for Computational Linguistics. Meeting · 2025
    Article
  12. Article
  13. Large language models in critical care.Journal of intensive medicine · 2025
    Review
  14. Unstructured Electronic Health Records of Dysphagic Patients Analyzed by Large Language Models.IEEE journal of translational engineering in health and medicine · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Towards Reducing Diagnostic Errors with Interpretable Risk Prediction.Proceedings of the conference. Association for Computational Linguistics. North American Chapter. Meeting · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hiba AhsanNortheastern University, Boston, MA.
Denis Jered McInerneyNortheastern University, Boston, MA.
Jisoo KimBrigham and Women's Hospital, Boston, MA.
Christopher PotterBrigham and Women's Hospital, Boston, MA.
Geoffrey YoungBrigham and Women's Hospital, Boston, MA.
Silvio AmirNortheastern University, Boston, MA.
Byron C WallaceNortheastern University, Boston, MA.

Funding

A New Informatics Approach for Detection of Cerebrovascular AbnormalitiesR01LM013891 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI YOUNG, GEOFFREY · 2022 to 2025
$1.5M
Targeted Neural Text Summarization of Electronic Medical Records to Improve Imaging DiagnosticsR01LM013772 · NLM · NORTHEASTERN UNIVERSITY · PI WALLACE, BYRON CASEY, YOUNG, GEOFFREY · 2022 to 2024
$1.0M
NLM NIH HHS R01 LM013772NLM NIH HHS R01 LM013891
6 · The paper itself

Abstract

Unstructured data in Electronic Health Records (EHRs) often contains critical information-complementary to imaging-that could inform radiologists' diagnoses. But the large volume of notes often associated with patients together with time constraints renders manually identifying relevant evidence practically infeasible. In this work we propose and evaluate a zero-shot strategy for using LLMs as a mechanism to efficiently retrieve and summarize unstructured evidence in patient EHR relevant to a given query. Our method entails tasking an LLM to infer whether a patient has, or is at risk of, a particular condition on the basis of associated notes; if so, we ask the model to summarize the supporting evidence. Under expert evaluation, we find that this LLM-based approach provides outputs consistently preferred to a pre-LLM information retrieval baseline. Manual evaluation is expensive, so we also propose and validate a method using an LLM to evaluate (other) LLM outputs for this task, allowing us to scale up evaluation. Our findings indicate the promise of LLMs as interfaces to EHR, but also highlight the outstanding challenge posed by "hallucinations". In this setting, however, we show that model confidence in outputs strongly correlates with faithful summaries, offering a practical means to limit confabulations.

Identifiers

PMID39224857
PMCPMC11368037

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.