Evidence map›Paper›PMID 39224805›Full record

ArticleFrontiers in oncology2024

Persistent primary hyperparathyroidism caused by an ectopic adenoma in the piriform sinus: case report and review of the literature.

Chiara Sardella, Veronica Seccia, Massimo Giambalvo, Laura Pierotti, Elisa Dinoi, Simone Della Valentina, Elena Pardi, Gabriele Materazzi, Iacopo Dallan, Stefano Berrettini and 1 more

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chiara SardellaEndocrine Unit, University Hospital of Pisa, Pisa, Italy.
Veronica SecciaOtolaryngology, Audiology and Phoniatric Operative Unit, University Hospital of Pisa, Pisa, Italy.
Massimo GiambalvoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Laura PierottiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Elisa DinoiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Simone Della ValentinaDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Elena PardiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Gabriele MaterazziDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Iacopo DallanSkull Base and Rhino-Orbital Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Stefano BerrettiniOtolaryngology, Audiology and Phoniatric Operative Unit, University Hospital of Pisa, Pisa, Italy.
Filomena CetaniEndocrine Unit, University Hospital of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder in which surgery is the only curative therapy. Ectopic parathyroid adenoma in the pyriform sinus resulting from a pathological migration of parathyroid glands along the embryological development is a rare cause of PHPT. We describe a case of a persistent primary hyperparathyroidism after previous unsuccessful surgery due to an ectopic parathyroid adenoma within the pyriform sinus and we review the previous reports on this issue. Case presentation: A 62-year-old woman was referred for persistent hypercalcemia following unsuccessful cervical exploratory surgery. Cervical ultrasound did not detect any parathyroid abnormalities. At variance, Conclusions: The ectopic parathyroid adenoma in the pyriform sinus is so uncommon that only fourteen cases have been reported. However, the pyriform sinus should be considered a possible location of ectopic parathyroid glands, especially in the setting of persistent or recurrent PHPT after parathyroid surgery.

Indexed as

ectopic parathyroid adenomaparathyroid glandspersistent primary hyperparathyroidismpyriform sinustransoral robotic parathyroidectomy

Identifiers

PMID39224805
PMCPMC11366630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.