Evidence map›Paper›PMID 39224671›Full record

ArticleIJU case reports2024

A case of double-negative prostate cancer with

Hiroki Tanaka, Soichiro Yoshida, Satoru Aoyama, Sadakatsu Ikeda, Junko Kunieda, Kenichi Ohashi, Shohei Fukuda, Yuma Waseda, Hajime Tanaka, Yasuhisa Fujii

Abstract readCase Reports
In one paragraph

Article in IJU case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroki TanakaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Soichiro YoshidaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.ORCID https://orcid.org/0000-0003-2757-8083
Satoru AoyamaDepartment of Precision Cancer Medicine Tokyo Medical and Dental University Tokyo Japan.
Sadakatsu IkedaDepartment of Precision Cancer Medicine Tokyo Medical and Dental University Tokyo Japan.
Junko KuniedaDepartment of Pathology Tokyo Medical and Dental University Tokyo Japan.
Kenichi OhashiDepartment of Pathology Tokyo Medical and Dental University Tokyo Japan.
Shohei FukudaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Yuma WasedaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Hajime TanakaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.ORCID https://orcid.org/0000-0003-3632-2901
Yasuhisa FujiiDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Double-negative prostate cancer, an androgen receptor-independent prostate cancer without features of neuroendocrine tumors, is refractory to treatment but could be an ideal candidate for individualized treatment. Case presentation: An 85-year-old patient with metastatic castration-resistant prostate cancer without prostate-specific antigen progression presented with local recurrence and liver and lung metastases 6 months after orchiectomy and apalutamide. A liver tumor biopsy led to a diagnosis of double-negative prostate cancer. FoundationOne Conclusion: Sequential use of olaparib and pembrolizumab may be effective for double-negative prostate cancer with

Indexed as

androgen receptor antagonistsdiffusion magnetic resonance imagingDNA mutational analysisgenes, BRCA2prostatic neoplasms, castration‐resistant

Identifiers

PMID39224671
PMCPMC11366435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.