ArticleIJID regions2024
Malnutrition is a risk factor for tuberculosis disease among household contacts: A case-control study in Uganda.
Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Trial
- Determinants of underweight and overweight/obesity among people with tuberculosis in Kampala, Uganda: A cross-sectional study.PloS one · 2026Article
- Article
- A roadmap for integrating nutritional assessment, counselling, and support into the care of people with tuberculosis.The Lancet. Global health · 2025Review
- Association Between Malnutrition and Multi-Drug Resistant Bacterial Infections in Neurosurgical Intensive Care Unit Patients.Infection and drug resistance · 2025Article
- One out of every three adult TB patients suffered from undernutrition in conflict affected Southern Ethiopia: a multicenter facility-based cross-sectional study.Frontiers in epidemiology · 2025Article
- Malnutrition and unsuccessful tuberculosis treatment among people with multi-drug resistant tuberculosis in Uganda: A retrospective analysis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Household contacts (HHCs) of persons with tuberculosis (TB) including rifampicin-resistant or multi-drug-resistant TB (RR/MDR-TB) are at risk for TB infection. We investigated whether index patient-level clinical and socio-demographic factors of persons with MDR-TB are associated with TB disease among their HHCs in Uganda. Methods: We designed an unmatched case-control study. Cases were HHCs of persons with MDR-TB that had TB disease while controls were a random sample of HHCs of persons with MDR-TB that had no TB disease. The case-to-control ratio was 1:3. We identified the factors that significantly differed between the cases and controls in a multivariable binary logistic regression analysis and reported the odds ratio (OR) and 95% confidence interval (CI). Results: We found similar demographic and clinical characteristics among the 11 cases and 33 controls. In a multivariable analysis, malnutrition was significantly associated with being a case than a control (adjusted OR 5.01; 95% CI 1.18-24.83). Conclusion: Therefore, TB Control Programs should focus on identifying malnutrition among persons with MDR-TB and providing nutritional counseling and support to improve recovery, and potentially reduce household TB transmission and optimize treatment success. Additionally, rapid screening for TB and preventive therapy should be prioritized to reduce transmission.
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