Evidence map›Paper›PMID 39224416›Full record

ArticleEplasty2024

Decreased Use of Anti-Inflammatory Medications in Autoimmune Connective Tissue Disease Patients Following Breast Implant Removal: A National Analysis.

Jennifer K Shah, Daniel Najafali, Ethan Fung, Mallory Rowley, Kometh Thawanyarat, Priscila C Cevallos, Nathan Makarewicz, Karanvir S Raman, Rahim Nazerali

Abstract read
In one paragraph

Article in Eplasty, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer K ShahGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Daniel NajafaliCarle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois.
Ethan FungState University of New York, Upstate Medical University, Syracuse, New York.
Mallory RowleyInternal Medicine-Pediatrics, University of Rochester Medical Center, Rochester, New York.
Kometh ThawanyaratMedical College of Georgia at Augusta University, Augusta, Georgia.
Priscila C CevallosGeisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Nathan MakarewiczStanford University School of Medicine, Stanford, California.
Karanvir S RamanFaculty of Medicine, University of British Columbia, Vancouver, Canada.
Rahim NazeraliStanford University School of Medicine, Stanford, California.

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
NCATS NIH HHS UL1 TR001085
6 · The paper itself

Abstract

Background: Recent case studies demonstrate resolution of rheumatologic symptoms following implant explantation, raising concern around breast implant illness and associated inflammatory symptomatology. In patients with connective tissue disorders (CTD) and breast implants, we quantified the number of anti-inflammatory medications as a proxy for inflammation and disease burden before and after implant removal. Methods: Using the Clinformatics Data Mart Database, adult female patients from 2003 to 2021 were queried. Results: Of 1015 patients meeting criteria (mean age 56 ± 12 years), 821 (81%) filled prescriptions during the preoperative window, 753 (74%) filled during the perioperative window, and 735 (73%) filled during the postoperative window. Patients filled significantly fewer postoperative prescriptions than preoperative prescriptions ( Conclusions: We found a significant decrease in filled anti-inflammatory prescriptions in patients with known CTD following implant removal, suggesting that breast implant removal may help diminish inflammatory symptomology in predisposed patients.

Indexed as

Autoimmunebreast implant illnessConnective Tissue DiseaseExplantationMedications

Identifiers

PMID39224416
PMCPMC11367158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.