Evidence map›Paper›PMID 39224093›Full record

ArticleEuropean heart journal. Imaging methods and practice2024

Differential culprit plaque morphology in acute coronary syndrome: a comparison between very young patients (≤35 years) and older counterparts using optical coherence tomography.

Gaurav Chaudhary, Basant Gupta, Shubhajeet Roy, Sharad Chandra, Akhil Sharma, Akshyaya Pradhan, Monika Bhandari, Pravesh Vishwakarma, Rishi Sethi, Sudhanshu Kumar Dwivedi and 7 more

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Unmet Need for Deep Diving into Intracoronary Imaging.Anatolian journal of cardiology · 2025
    Article
  2. Cardiovascular imaging in 2024: review of current research and innovations.European heart journal. Imaging methods and practice · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Gaurav ChaudharyDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Basant GuptaDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Shubhajeet RoyKing George Medical University, Lucknow, Uttar Pradesh, India.
Sharad ChandraDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Akhil SharmaDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Akshyaya PradhanDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Monika BhandariDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Pravesh VishwakarmaDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Rishi SethiDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sudhanshu Kumar DwivediDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Vinit BaliyanDepartment of Radiology, Division of Cardiovascular Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Prachi SharmaDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Vikash JaiswalDepartment of Cardiovascular Research, Larkin Community Hospital, South Miami, FL, USA.ORCID https://orcid.org/0000-0002-2021-1660
Abhishek SinghDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Ayush ShuklaDepartment of Cardiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sajina ShresthaDepartment of Medicine, KIST Medical College, Imadol, Patan, M86M+H4W, Mahalaxmi 44700, Nepal.
Alessia GimelliDepartment of Imaging, Fondazione Toscana 'Gabriele Monasterio', Pisa, Italy.ORCID https://orcid.org/0000-0003-3378-1723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Underlying mechanisms responsible for acute coronary syndrome (ACS) in young patients compared with older counterparts are yet to be explored with optical coherence tomography (OCT). This study aims to explore underlying mechanisms of ACS in ≤35- (very young) and >35-year-old (older counterparts) ACS patients using OCT. Methods and results: This was a prospective, single-centre, investigational study. Patients were divided into groups according to age (≤35 and >35 years) and further subdivided according to the underlying mechanism i.e. plaque rupture (PR) and plaque erosion (PE). A total of 93 patients were analysed. Thin-cap fibroatheroma (TCFA) was significantly higher among older counterparts than very young patients for both PR (80.0% vs. 31.8%, Conclusion: Frequency of TCFA, microchannels, macrophages, and intimal thickness was significantly higher in older ACS patients compared with very young patients. However, fibrous cap thickness was significantly greater in very young ACS patients compared with older patients.

Indexed as

acute coronary syndromeintimal thicknessoptical coherence tomographyplaque erosionplaque rupturethin-cap fibroatheroma

Identifiers

PMID39224093
PMCPMC11367943

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