Evidence map›Paper›PMID 39223760›Full record

ArticleEarly intervention in psychiatry2025

An Item Response Theory Analysis of the Psychosis Screening Questionnaire in Ethiopia.

Mahlet Yared, Hannah H Kim, Amantia Ametaj, Melkam Alemayehu, Anne Stevenson, Barkot Milkias, Engida Girma, Bizu Gelaye, Solomon Teferra

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Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mahlet YaredDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-7258-379X
Hannah H KimDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Amantia AmetajDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Melkam AlemayehuDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Anne StevensonDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-7890-3291
Barkot MilkiasDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0001-6596-9689
Engida GirmaDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Bizu GelayeDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Solomon TeferraDepartment of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Funding

1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesU01MH125047 · NIMH · BROAD INSTITUTE, INC. · PI MARTIN, ALICIA, NEALE, BENJAMIN MICHAEL · 2020 to 2024
$11.5M
Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
2/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African AncestriesU01MH125045 · NIMH · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI KOENEN, KARESTAN C · 2020 to 2024
$3.1M
Psychosis Genetics Research in Africa: Building Capacity by Investing in PeopleR01MH120642 · NIMH · BROAD INSTITUTE, INC. · PI AKENA, DICKENS HOWARD, CHIBNIK, LORI BETH · 2019 to 2023
$3.1M
Barry R. and Irene Tilenius Bloom Fellowship FundNIMH NIH HHS R01 MH120642NIMH NIH HHS T32 MH017119NIMH NIH HHS U01 MH125045NIMH NIH HHS U01 MH125047Stanley Center for Psychiatric Research, Broad Institute R01MH120642United States' National Institute of Mental Health NIMH T32MH017199United States' National Institute of Mental Health NIMH U01MH125047United States' National Institute of Mental Health U01MH125045
6 · The paper itself

Abstract

aimFew psychosis screening instruments have been tested for use in Africa, yet appropriate tools can increase the detection of self-reported psychotic symptoms, improve the detection of psychosis and impact its prognosis.

methodThe construct validity and factor structure of Psychosis Screening Questionnaire (PSQ) were tested with confirmatory factor analysis (CFA) and item response theory (IRT) in a sample of 1928 Ethiopian adults without any history of psychosis. We tested a unidimensional model with and without an item on mania. For IRT, unidimensional latent structure one-parameter logistic (1PL) and two-parameter (2PL) logistic models were tested and compared for relative fit using a likelihood-ratio test. RESULT AND DISCUSSION: The prevalence of lifetime positive screens was 2.8% in an Ethiopian sample of adults from a general medical setting. A unidimensional model demonstrated good fit for the PSQ, (CFI = 0.993, TLI = 0.986 and RMSEA = 0.025). For IRT, a 2PL model was the best fitting one. IRT tests of item difficulty and discrimination parameters showed that paranoia had the highest discrimination

conclusionThe PSQ is found to have good construct validity in screening for psychosis among Ethiopian adults. Future studies may focus on the diagnostic validity of the PSQ comparing it with a structured clinical interview.

Indexed as

Psychiatric Status Rating ScalesPsychotic DisordersAdolescentAdultEthiopiaFactor Analysis, StatisticalFemaleHumansMaleMass ScreeningMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesYoung Adultconfirmatory factor analysisconstruct validityEthiopiaitem response theoryPsychosis Screening Questionnaire

Identifiers

PMID39223760
PMCPMC11729251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.