Evidence map›Paper›PMID 39223720›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2025

Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis.

Ian Hennessee, Kaitlin Benedict, Nathan C Bahr, Shari R Lipner, Jeremy A W Gold

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. [Influencing Factors for Secondary Fungal Infections in Systemic Lupus Erythematosus].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ian HennesseeMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0001-8807-9566
Kaitlin BenedictMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0003-0458-2493
Nathan C BahrDivision of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Shari R LipnerDepartment of Dermatology, Weill Cornell Medicine, New York, New York, USA.
Jeremy A W GoldMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

Novel Diagnostic Development for TB Meningitis and HistoplasmosisK23NS110470 · NINDS · UNIVERSITY OF MINNESOTA · PI BAHR, NATHAN · 2019 to 2023
$1.0M
NIH HHS K23 NS110470NINDS NIH HHS K23 NS110470
6 · The paper itself

Abstract

In a commercial claims database analysis, <0.5% of patients with inflammatory bowel disease or rheumatoid arthritis developed an invasive fungal infection (IFI) within 1 year of initiating tumor necrosis factor-alpha therapy. Histoplasmosis was the most common IFI type. Overall IFI incidence varied based on region, underlying conditions, and use of certain immunosuppressive medications.

Indexed as

Arthritis, RheumatoidInflammatory Bowel DiseasesInvasive Fungal InfectionsTumor Necrosis Factor-alphaAdultAgedFemaleHumansIncidenceMaleMiddle AgedRisk FactorsYoung AdultTumor Necrosis Factor-alphahistoplasmosisinflammatory bowel diseaseinvasive fungal infectionsrheumatoid arthritisTNF-α inhibitors

Identifiers

PMID39223720
PMCPMC11848264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.