ArticleNature metabolism2024
Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome.
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In one paragraph
Article in Nature metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed.
- Mitochondria-Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Horizontal mitochondrial transfer and mitochondrial transplantation in skin: protection against UVR-induced ROS damage and enhancement of cell proliferation and wound healing.Journal of translational medicine · 2026Article
- Preparation of ENBSe-based photoredox catalysts for ONature protocols · 2026Review
- Myeloid cell replacement induces intercellular mitochondrial transfer and restores metabolism in a mouse model of mitochondrial disease.Nature communications · 2026Article
- Xenogeneic Mitochondrial Transplantation Improves Selected Age-Associated Phenotypes in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Plant-derived mitochondria mitigate aging-related neurodegeneration by reprogramming microglial mitochondrial energy metabolism.Translational neurodegeneration · 2026Article
- Novel Allogeneic Mitochondria and Associated Organelle Complex Treatment Prevents Myocardial Ischemia-Reperfusion Injury Through Anti-Apoptotic Effects.JACC. Asia · 2026Article
- Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics.Annals of neurology · 2026Article
- The progress of mitochondrial function and transfer in stem cell regulation and therapy.Journal of physiology and biochemistry · 2026Review
- Article
- Mitochondrial Transfer in the Tumor Microenvironment.Cancer science · 2026Review
- Article
- Emerging Design Principles at the Forefront of Mitochondrial Transplantation Using Engineering Methodologies: Current Achievements and Future Directions.Chemical biology & drug design · 2026Review
- Mitochondria transfer: intercellular communication and tumor microenvironment dynamics.Cell communication and signaling : CCS · 2026Review
- Cardiomyocyte derived extracellular mitochondria in activation of macrophages during oxidative stress.Cardiovascular research · 2026Article
- Targeting organelle function in T cells for cancer immunotherapy.Nature reviews. Immunology · 2026Review
- Characterization of aMolecular genetics and metabolism reports · 2026Article
- Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Assessment of mitochondrial viability under calcium Stress: Insights for mitochondrial transplantation.Mitochondrion · 2026Article
- Mitochondria transfer in tissue homeostasis and diseases.International journal of biological sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Ritsuko Nakai *Department of Hematology and Oncology, Graduate School of Medicine, Osaka University, Suita, Japan.ORCID http://orcid.org/0000-0002-7891-4879
Stella Varnum *Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-4671-7088
Rachael L FieldDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0009-0003-1717-9756
Henyun ShiDepartment of Hematology and Oncology, Graduate School of Medicine, Osaka University, Suita, Japan.
Rocky GiwaDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Wentong JiaDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Samantha J KrysaDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Eva F CohenDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Nicholas BorcherdingDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Russell P SanetoNeuroscience Institute, Center for Integrated Brain Research, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7250-2347
Rick C TsaiLUCA Science, Tokyo, Japan.ORCID http://orcid.org/0009-0000-5816-7303
Masashi SuganumaLUCA Science, Tokyo, Japan.ORCID http://orcid.org/0009-0006-8639-1365
Hisashi OhtaLUCA Science, Tokyo, Japan.
Takafumi YokotaDepartment of Hematology and Oncology, Graduate School of Medicine, Osaka University, Suita, Japan. yokotat@oici.jp.ORCID http://orcid.org/0000-0001-9358-8947
Jonathan R BrestoffDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. brestoff@wustl.edu.ORCID http://orcid.org/0000-0002-7018-7400
Funding
The North American Mitochondrial Disease Consortium (NAMDC)U54NS078059 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HAAS, RICHARD H · 2011 to 2023
$17.5MHarnessing mitochondria transfer pathways to ameliorate Leigh Syndrome-like diseaseR01NS134932 · NINDS · WASHINGTON UNIVERSITY · PI Jonathan R Brestoff · 2024 to 2026
$1.8MAmerican Heart Association (American Heart Association, Inc.) 24POST1244220American Heart Association (American Heart Association, Inc.) 24PRE1189775Burroughs Wellcome Fund (BWF) CAMS #1019648MEXT | Japan Science and Technology Agency (JST) JPMJSP #2138MEXT | Japan Society for the Promotion of Science (JSPS) 20K17379MEXT | Japan Society for the Promotion of Science (JSPS) 21K08415MEXT | Japan Society for the Promotion of Science (JSPS) 22K16322NINDS NIH HHS R01 NS134932NINDS NIH HHS U54 NS078059U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 1R01NS134932U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 5U54-NS078059-12
Abstract
Mitochondria transfer is a recently described phenomenon in which donor cells deliver mitochondria to acceptor cells
Indexed as
Leigh DiseaseMitochondriaAnimalsDisease Models, AnimalElectron Transport Complex IHumansMiceMice, KnockoutElectron Transport Complex INdufs4 protein, mouse
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.