Evidence map›Paper›PMID 39223184›Full record

ArticleScientific reports2024

Green synthesis of copper oxide nanoparticles using walnut shell and their size dependent anticancer effects on breast and colorectal cancer cell lines.

Hanieh Abdollahzadeh, Yaghub Pazhang, Asghar Zamani, Yousef Sharafi

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hanieh AbdollahzadehDepartment of Biology, Faculty of Sciences, Urmia University, Urmia, Iran.
Yaghub PazhangDepartment of Biology, Faculty of Sciences, Urmia University, Urmia, Iran. y.pazhang@urmia.ac.ir.ORCID 0000-0002-0572-2980
Asghar ZamaniDepartment of Nanotechnology, Faculty of Chemistry, Urmia University, Urmia, Iran.
Yousef SharafiDryland Agricultural Research Institute, Agricultural Research, Education and Extension Organization(AREEO), Maragheh, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal oxide nanoparticles(NPs) contain unique properties which have made them attractive agents in cancer treatment. The CuO nanoparticles were green synthesized using walnut shell powder in different calcination temperatures (400°, 500°, 700°, and 900 °C). The CuO nanoparticles are characterized by FTIR, XRD, BET, SEM and DLS analyses. SEM and DLS analyses showed that by increasing the required calcination temperature for synthesizing the NPs, their size was increased. DPPH analysis displayed no significant anti-oxidative properties of the CuO NPs. The MTT analysis showed that all synthesized CuO NPs exhibited cytotoxic effects on MCF-7, HCT-116, and HEK-293 cell lines. Among the CuO NPs, the CuO-900 NPs showed the least cytotoxic effect on the HEK-293 cell line (IC

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsColorectal NeoplasmsCopperGreen Chemistry TechnologyJuglansMetal NanoparticlesAntioxidantsCell Line, TumorCell SurvivalFemaleHCT116 CellsHEK293 CellsHumansMCF-7 CellsAntineoplastic AgentsAntioxidantsCoppercuprous oxideTumor Suppressor Protein p53ApoptosisCancer therapyCuO nanoparticlesGreen synthesisNrf-2p53Walnut shell

Identifiers

PMID39223184
PMCPMC11369244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.