Evidence map›Paper›PMID 39222967›Full record

ArticleBMJ open respiratory research2024

Thoughtful prescription of inhaled medication has the potential to reduce inhaler-related greenhouse gas emissions by 85.

Ville Vartiainen, Ashley A Woodcock, Alex Wilkinson, Christer Janson, Unnur Björnsdóttir, Tari Haahtela, Lauri Lehtimäki

Abstract read
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Article in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ville VartiainenDepartment of Pulmonary Medicine, Helsinki University Hospital Heart and Lung Center, Helsinki, Finland ville.vartiainen@helsinki.fi.ORCID 0000-0002-9833-6965
Ashley A WoodcockUniversity NHS Foundation Trust, UK, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Alex WilkinsonRespiratory Department, East and North Hertfordshire NHS Trust, Stevenage, UK.ORCID 0000-0002-1808-3663
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-5093-6980
Unnur BjörnsdóttirDepartment of Allergy and Pulmonary Medicine, University Hospital Iceland, Reykjavik, Iceland.
Tari HaahtelaSkin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Lauri LehtimäkiAllergy Centre, Tampere University Hospital, Tampere, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBoth physicians and patients are increasingly aware of the environmental impacts of medication. The shift of treatment paradigm towards MART-treatment (Maintenance and Reliever Therapy) in asthma affects the treatment-related emissions. The carbon footprint of inhaled medication is also tied to the type of the device used. Today the most commonly used propellant-containing pressurised metered-dose inhalers (pMDIs) have a carbon footprint typically 20-40-fold higher than propellant-free dry powder inhalers (DPIs) and soft mist inhalers.

methodsWe analysed the carbon footprint of inhaled medications in Europe using published life cycle analyses of marketed inhalers and comprehensive 2020 European sales data. In addition, we give an estimate on treatment-related emissions of different treatment regimens on Global Initiative for Asthma (GINA) step 2.

resultsThere is potential to reduce the carbon footprint of inhaled medications by 85% if DPIs are preferred over pMDIs. Emissions from pMDIs in the EU were estimated to be 4.0 megatons of carbon dioxide equivalent (MT CO DISCUSSION: There has been an urgent call for healthcare to reduce its carbon footprint for appropriate patients with asthma and chronic obstructive pulmonary disease (COPD), changing to non-propellant inhalers can reduce the carbon footprint of their treatment by almost 20-fold.

Indexed as

AsthmaCarbon FootprintDry Powder InhalersGreenhouse GasesMetered Dose InhalersAdministration, InhalationAnti-Asthmatic AgentsEuropeHumansAnti-Asthmatic AgentsGreenhouse Gasesasthmainhaler devices

Identifiers

PMID39222967
PMCPMC11428981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.