ArticleThe Lancet. Global health2024
Ebola disease outbreak caused by the Sudan virus in Uganda, 2022: a descriptive epidemiological study.
Article in The Lancet. Global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Impact of Diagnostic Delays and Timeliness of Response on Ebola Disease outbreak-level case-fatality Ratios in Uganda (2000-2023): a Rapid Systematic Review and meta-analysis.Journal of epidemiology and global health · 2025Pooled it
- Ebola Virus Disease in the Era of One Health and Global Preparedness: Evolving Epidemiology, Genomic Surveillance, and Future Challenges.Infectious disease reports · 2026Review
- Bundibugyo virus detection during an Ebola virus disease outbreak in the democratic Republic of the Congo: an urgent call for action.Tropical medicine and health · 2026Article
- Identification of a unique humoral immune signature of Sudan ebolavirus persistence in human survivors.Research square · 2026Article
- Article
- Achievements and Challenges in Therapy and Vaccines Development of Viral Hemorrhagic Fevers: An Up-to-Date Review.Pharmaceutics · 2026Review
- Understanding the Rift Valley fever exposure risk: A comparative perspective from a multi-country study in East and Central Africa, 2021-24.PLoS neglected tropical diseases · 2026Article
- Ebola virus disease: A persistent challenge in global health security.Open veterinary journal · 2026Review
- Investigating the Sudan virus outbreak in Uganda through the deployment of a mobile laboratory.BMC infectious diseases · 2026Article
- High-Resolution Mapping of Environmental Suitability for Reported Ebola Spillover Events in Uganda to Inform Surveillance and Preparedness.Journal of tropical medicine · 2026Article
- Ebola disease stigma: mixed methods insights from the 2022 Sudan ebolavirus outbreak.BMJ open · 2025Article
- Global stability for a cumulative release Ebola epidemic model from the corpses and infected individuals.Infectious Disease Modelling · 2025Article
- The Silent Risk of Sudan Virus: A Review Addressing Global Health Vulnerabilities.Health science reports · 2025Article
- Article
- Modeling Case Burden and Duration of Sudan Ebola Virus Disease Outbreak in Uganda, 2022.Emerging infectious diseases · 2025Article
- Review
- Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions.Health science reports · 2025Article
- Epidemiology and Genetic Characterization of Distinct Ebola Sudan Outbreaks in Uganda.Infectious disease reports · 2025Article
- Barriers to community engagement during the response to an Ebola virus disease outbreak in Uganda.BMJ global health · 2025Article
- Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1.Communications biology · 2025Article
Corrections and comments
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Authors and funding
34 authors.
Funding
Abstract
backgroundUganda has had seven Ebola disease outbreaks, between 2000 and 2022. On Sept 20, 2022, the Ministry of Health declared a Sudan virus disease outbreak in Mubende District, Central Uganda. We describe the epidemiological characteristics and transmission dynamics.
methodsFor this descriptive study, cases were classified as suspected, probable, or confirmed using Ministry of Health case definitions. We investigated all reported cases to obtain data on case-patient demographics, exposures, and signs and symptoms, and identified transmission chains. We conducted a descriptive epidemiological study and also calculated basic reproduction number (R
findingsBetween Aug 8 and Nov 27, 2022, 164 cases (142 confirmed, 22 probable) were identified from nine (6%) of 146 districts. The median age was 29 years (IQR 20-38), 95 (58%) of 164 patients were male, and 77 (47%) patients died. Symptom onsets ranged from Aug 8 to Nov 27, 2022. The case fatality rate was highest in children younger than 10 years (17 [74%] of 23 patients). Fever (135 [84%] of 160 patients), vomiting (93 [58%] patients), weakness (89 [56%] patients), and diarrhoea (81 [51%] patients) were the most common symptoms; bleeding was uncommon (21 [13%] patients). Before outbreak identification, most case-patients (26 [60%] of 43 patients) sought care at private health facilities. The median incubation was 6 days (IQR 5-8), and median time from onset to death was 10 days (7-23). Most early cases represented health-care-associated transmission (43 [26%] of 164 patients); most later cases represented household transmission (109 [66%]). Overall R
interpretationDespite delayed detection, the 2022 Sudan virus disease outbreak was rapidly controlled, possibly thanks to a low R
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