Evidence map›Paper›PMID 39222340›Full record

ArticleJournal of medical microbiology2024

Evaluating the accuracy of the MBT Lipid Xtract Kit for assessing colistin resistance in comparison to broth microdilution.

Calvin Ka-Fung Lo, Gordon Ritchie, Jennifer Bilawka, Leah Gowland, Samuel D Chorlton, Willson Jang, Nancy Matic, Marc G Romney, Aleksandra Stefanovic, Christopher F Lowe

Abstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Performance evaluation of a novel MBT LipidART module (Bruker Daltonics) for detection of colistin resistance in Escherichia coli and Klebsiella pneumoniae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Calvin Ka-Fung LoDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Gordon RitchieDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Jennifer BilawkaDivision of Medical Microbiology and Virology, Providence Health Care, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Leah GowlandDivision of Medical Microbiology and Virology, Providence Health Care, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Samuel D ChorltonBugSeq Bioinformatics, Vancouver, British Columbia, Canada.
Willson JangDivision of Medical Microbiology and Virology, Providence Health Care, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Nancy MaticDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Marc G RomneyDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Aleksandra StefanovicDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Christopher F LoweDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin resistance testing methods such as broth microdilution (BMD) are time-consuming and labour intensive for clinical laboratories. MBT Lipid Xtract Kit on MALDI Biotyper Sirius System (Bruker, Billerica, MA, USA) utilizes lipidomic analysis to identify specific cell wall modifications associated with colistin resistance. We compared MBT to BMD (ComASP Colistin, Liofilchem) across 36 Gram-negative isolates (non-resistant MIC ≤2 µg ml

Indexed as

Anti-Bacterial AgentsColistinDrug Resistance, BacterialMicrobial Sensitivity TestsEscherichia coliGram-Negative BacteriaHumansWhole Genome SequencingAnti-Bacterial AgentsColistinBMDcolistinlipidomicsmcr-1resistance screeningsusceptibility testing

Identifiers

PMID39222340
PMCPMC11368154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.