ArticleIntensive care medicine2024
Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study.
Article in Intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Clinical randomized trial of vitamin D and C supplementation in critically ill patients with respiratory failure.Nutrition journal · 2025Trial
- Low versus high positive end expiratory pressure in noninvasive ventilation for hypoxemic respiratory failure: a multicenter randomized controlled trial.Intensive care medicine · 2025Trial
- Body mass index and hospital mortality in mechanically ventilated patients with acute hypoxaemic respiratory failure: A retrospective cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Rethinking phenotyping in acute respiratory failure: systemic inflammation can be infectious or noninfectious.Intensive care medicine · 2026Article
- Update on acute respiratory failure.Intensive care medicine · 2026Article
- Evaluation of Quantitative Computed Tomography Indices in Patients with Pneumonia and Acute Respiratory Failure in the Intensive Care Unit (ICU).Diagnostics (Basel, Switzerland) · 2026Article
- Validation of PaO2:FiO2 for predicting hospital mortality in critically ill patients with acute hypoxaemic respiratory failure: a retrospective binational registry-based study.Critical care science · 2026Article
- Article
- Intra-hospital transport of adult critically ill patients treated with high flow nasal cannula oxygen: a prospective observational multicenter study.Annals of intensive care · 2025Article
- Review
- Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study.Journal of intensive care · 2025Article
- Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.Frontiers in pharmacology · 2025Article
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Authors and funding
9 authors.
Funding
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Abstract
purposeAcute hypoxaemic respiratory failure (AHRF) is a common reason for intensive care unit (ICU) admission. However, patient characteristics, outcomes, and trends over time are unclear. We describe the epidemiology and outcomes of patients with AHRF over time.
methodsIn this binational, registry-based study from 2005 to 2022, we included all adults admitted to an Australian or New Zealand ICU with an arterial blood gas within the first 24 h of ICU stay. AHRF was defined as a partial pressure of oxygen/inspired oxygen ratio (PaO
resultsOf 1,560,221 patients, 826,106 (52.9%) were admitted with or developed AHRF within the first 24 h of ICU stay. Of these 826,106 patients, 51.4% had mild, 39.3% had moderate, and 9.3% had severe AHRF. Compared to patients without AHRF (5.3%), patients with mild (8%), moderate (14.2%) and severe (29.9%) AHRF had higher in-hospital mortality rates. As PaO
conclusionThe healthcare burden due to AHRF may be larger than expected, and mortality rates remain high in severe AHRF. Although mortality has decreased over time, this may reflect improvements in ICU care in general, rather than specifically in AHRF. More research is required to earlier identify AHRF and stratify these patients at risk of deterioration early, and to validate our findings.
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