Evidence map›Paper›PMID 39221760›Full record

ArticlePsychiatry and clinical neurosciences2024

The longitudinal patterns of depression subtypes and stressors in depression severity in the Canadian longitudinal study on aging (CLSA).

Yingying Su, Muzi Li, Norbert Schmitz, Xiangfei Meng

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Article in Psychiatry and clinical neurosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Yingying SuDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-7540-2026
Muzi LiDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.
Norbert SchmitzDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.
Xiangfei MengDepartment of Psychiatry, McGill University, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-0857-1305

Funding

CIHR 23ca014
6 · The paper itself

Abstract

aimThe current study aims to characterize the longitudinal patterns of depression subtypes and investigate the associations among the stability of depression subtypes, COVID-19-related stressors, and depression severity.

methodsThe study utilized data from the Canadian Longitudinal Study on Aging, which is a national, long-term study of Canadian adults aged 45 and older (n = 12,957). Latent profile analysis was used to identify latent depression subtypes. Latent transition analysis was then applied to assess the stability of these subtypes over time. Hierarchical multivariate linear regression was used to explore the relationships among these identified depression subtypes, COVID-19-related stressors, and depression severity among males and females, respectively.

resultsDistinct depression subtypes were identified. Except for atypical depression, other depression subtypes showed greater stability over time. We also found that melancholic depression (B = 9.432) and typical depression (B = 6.677) were strongly associated with depression severity during the pandemic. Health-related stressors (B = 0.840), conflict (B = 3.639), difficulties accessing resources (B = 0.927), separation from family (B = 0.840), and caregiving experience (B = 0.764), were significantly associated with increased depression severity. Sex-specific analyses also revealed differences in the associations between stressors and depression severity between males and females.

conclusionsThis study contributes valuable insights into the latent clustering of depression subtypes and their stability. Stressors were associated with increased depression severity, with distinct associations observed among males and females. These findings have implications for targeted early interventions and integrated clinical management strategies by providing the evidence base for tailored mental health care during and after the pandemic.

Indexed as

COVID-19DepressionSeverity of Illness IndexStress, PsychologicalAgedAged, 80 and overAgingCanadaFemaleHumansLongitudinal StudiesMaleMiddle AgedSex Factorsatypical depressionCOVID‐19melancholiastabilitystress

Identifiers

PMID39221760
PMCPMC11804913

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.